Evidence map›Paper›PMID 41753476›Full record

ReviewMaterials (Basel, Switzerland)2026

Digital Manufacturing of Calcium Phosphate-Based Dental Materials: From Design to Clinical Use.

Valentin Lamasanu, Ionut Luchian, Dragos Ioan Virvescu, Teona Tudorici, Zinovia Surlari, Dana Gabriela Budala, Florinel Cosmin Bida, Oana Maria Butnaru, Mihaela Scurtu, Andrei Georgescu and 2 more

Abstract readReview
In one paragraph

Review in Materials (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Valentin LamasanuGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Ionut LuchianGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0003-0017-9672
Dragos Ioan VirvescuGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0009-0005-6872-179X
Teona TudoriciGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Zinovia SurlariGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0009-0009-5914-2891
Dana Gabriela BudalaGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0003-2312-6987
Florinel Cosmin BidaGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0009-0001-0319-0538
Oana Maria ButnaruGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0002-7404-399X
Mihaela ScurtuGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.
Andrei GeorgescuGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0000-0001-7407-844X
Nicoleta IoanidGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.ORCID 0009-0003-7558-3730
Monica Silvia TatarciucGrigore T. Popa University of Medicine and Pharmacy, 700115 Iasi, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calcium phosphate-based materials are widely used in dental applications due to their bioactivity and compositional similarity to mineralized tissues. This narrative review synthesizes the peer-reviewed literature published between 2014 and 2024 identified using Scopus, Web of Science, and PubMed, with a specific focus on digitally manufactured calcium phosphate-based dental materials. This review integrates evidence on calcium phosphate phase chemistry and advanced material systems, material configurations compatible with digital workflows and digital manufacturing routes. Emphasis is placed on how fabrication parameters and post-processing-particularly thermal treatment and densification-affect phase composition, microstructure/porosity, mechanical performance, and biological behavior. The current limitations reported in the literature are addressed, including material brittleness, dimensional instability during sintering, heterogeneity of fabrication protocols, and the lack of standardized evaluation methods. The restricted availability of long-term and clinically relevant evidence is also discussed in relation to translational applications. Future research should prioritize well-designed clinical studies to validate the use of digitally manufactured calcium phosphate-based materials in guided bone regeneration, socket preservation, and implant-related procedures.

Indexed as

additive manufacturingcalcium phosphate materialsdental biomaterialsdigital manufacturingmaterial processingscaffold

Identifiers

PMID41753476
PMCPMC12942147

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.