Evidence map›Paper›PMID 41753335›Full record

ReviewJournal of clinical medicine2026

Pulsed Field Ablation for Atrial Fibrillation: Contemporary Clinical Evidence and Real-World Experience in Redo Ablation.

Ioanna Koniari, Eleni Artopoulou, Scott Gall, Gavin S Chu, Rafail Koros, Maria Bozika, Kassiani-Maria Nastouli, Georgios Leventopoulos, Shajil Chalil, Aruna Arujuna

Abstract readReview
In one paragraph

Review in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Ioanna KoniariDepartment of Cardiology, University Hospital of Patras, 26504 Patras, Greece.ORCID 0000-0002-1033-5299
Eleni ArtopoulouKreiskrankenhausCalw, AkademischesLehrkrankenhaus Universität Tübingen, 72074 Tübingen, Germany.ORCID 0000-0002-7568-633X
Scott GallLancashire Cardiac Centre, Blackpool Teaching Hospitals NHS FT, Blackpool FY3 8NR, UK.
Gavin S ChuLancashire Cardiac Centre, Blackpool Teaching Hospitals NHS FT, Blackpool FY3 8NR, UK.
Rafail KorosDepartment of Cardiology, University Hospital of Patras, 26504 Patras, Greece.ORCID 0000-0002-6890-5127
Maria BozikaDepartment of Cardiology, University Hospital of Patras, 26504 Patras, Greece.ORCID 0009-0004-8215-427X
Kassiani-Maria NastouliDepartment of Cardiology, University Hospital of Patras, 26504 Patras, Greece.ORCID 0009-0005-3320-408X
Georgios LeventopoulosDepartment of Cardiology, University Hospital of Patras, 26504 Patras, Greece.
Shajil ChalilLancashire Cardiac Centre, Blackpool Teaching Hospitals NHS FT, Blackpool FY3 8NR, UK.
Aruna ArujunaLancashire Cardiac Centre, Blackpool Teaching Hospitals NHS FT, Blackpool FY3 8NR, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atrial fibrillation (AF) is the most common prevalent sustained arrhythmia and is associated with stroke, heart failure, and impaired health-related quality of life. Due to the complexity of the initiation and the persistence of AF, the pulmonary vein isolation (PVI) using thermal or laser energy is the most commonly applied ablation strategy. However, these thermal ablation modalities have several limitations, including a substantial risk of AF recurrence and collateral damage to tissues adjacent to the heart. Pulsed field ablation (PFA) is a novel non-thermal ablation technique in which high-voltage electric fields deliver short pulses, selectively affecting cardiomyocyte cell membranes. PFA has the potential to create myocardial lesions with minimal harm to non-cardiac tissues. Clinical studies have evaluated the safety and efficacy of PFA, examining its ability to prevent AF recurrence and its impact on surrounding structures, often in comparison with conventional PVI approaches. In this review, PFA clinical studies are discussed as well as our experience with the PFA use for redo atrial fibrillation ablation cases.

Indexed as

atrial fibrillationcatheter ablationelectroporationpulmonary vein isolationpulsed field ablation

Identifiers

PMID41753335
PMCPMC12941725

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.