Evidence map›Paper›PMID 41753213›Full record

ArticleJournal of clinical medicine2026

The Efficacy of IgM-Enriched Immunoglobulin (eIg) Administration for Treatment of Sepsis and Septic Shock in Adult Surgical Patients: A Single-Center, Retrospective, Observational Study.

Serena Spanò, Gabriella Licitra, Giada Cucciolini, Etrusca Brogi, Rita Martinelli, Francesco Cundari, Maria Giovanna Curci, Federico Coccolini, Stefano Busani, Giorgio Berlot and 4 more

Abstract read
In one paragraph

Article in Journal of clinical medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Serena SpanòDepartment of Anesthesia and Intensive Care, Azienda Ospedaliero Universitaria Pisana, 56126 Pisa, Italy.
Gabriella LicitraDepartment of Anesthesia and Intensive Care, Azienda Ospedaliero Universitaria Pisana, 56126 Pisa, Italy.ORCID 0000-0002-0547-3435
Giada CuccioliniDepartment of Anesthesia and Intensive Care, Azienda Ospedaliero Universitaria Pisana, 56126 Pisa, Italy.ORCID 0000-0001-9456-439X
Etrusca BrogiIntensive Care Unit, ASST Grande Ospedale Metropolitano Niguarda, 20162 Milan, Italy.ORCID 0000-0001-9010-7941
Rita MartinelliDepartment of Anesthesia and Intensive Care, Azienda Ospedaliero Universitaria Pisana, 56126 Pisa, Italy.
Francesco CundariDepartment of Anesthesia and Intensive Care, Azienda Ospedaliero Universitaria Pisana, 56126 Pisa, Italy.
Maria Giovanna CurciDepartment of Anesthesia and Intensive Care, Azienda Ospedaliero Universitaria Pisana, 56126 Pisa, Italy.
Federico CoccoliniGeneral, Emergency and Trauma Surgery Department, Pisa University Hospital, 56100 Pisa, Italy.
Stefano BusaniAnesthesia and Intensive Care Department, University Hospital of Modena, University of Modena, 41125 Reggio Emilia, Italy.ORCID 0000-0003-0150-4967
Giorgio BerlotAnesthesia and Intensive Care Department, University Hospital of Modena, University of Modena, 41125 Reggio Emilia, Italy.ORCID 0000-0002-9231-8555
Mattia BixioDepartment of Anesthesia and Intensive Care, Ospedale Policlinico San Martino, 16132 Genova, Italy.ORCID 0000-0002-9689-7195
Gianni BiancofioreDepartment of Transplant Anesthesia and Critical Care, University School of Medicine, 56126 Pisa, Italy.ORCID 0000-0002-3755-1434
Francesco CorradiDepartment of Anesthesia and Intensive Care, Azienda Ospedaliero Universitaria Pisana, 56126 Pisa, Italy.ORCID 0000-0002-5588-2608
Francesco ForforiDepartment of Anesthesia and Intensive Care, Azienda Ospedaliero Universitaria Pisana, 56126 Pisa, Italy.ORCID 0000-0001-8201-8076

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

average treatment effect (ATE)eIgICUIgGAM (Pentaglobin®)IgM-enriched immunoglobulinmortalitypropensity weighting score analysissepsissepsis dysfunctionseptic shocksurgical patients

Identifiers

PMID41753213
PMCPMC12941539

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.