Evidence map›Paper›PMID 41752957›Full record

ArticleLife (Basel, Switzerland)2026

Effect of Oxidative Stress Intensity on Inflammatory, Bone Turnover, and Haemostasis Biomarkers in Patients with Spinal Osteoarthritis.

Milan Mirković, Jelena Vekić, Nataša Bogavac-Stanojević, Jelena Kotur-Stevuljević, Neda Milinković, Anđelka Milić, Sanja Mirković, Ankica Vujović, Zoran Baščarević, Biljana Božić Nedeljković

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Milan MirkovićInstitute for Orthopedic Surgery "Banjica", 11000 Belgrade, Serbia.
Jelena VekićDepartment for Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0001-7445-0504
Nataša Bogavac-StanojevićDepartment for Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, 11000 Belgrade, Serbia.
Jelena Kotur-StevuljevićDepartment for Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0002-6980-3069
Neda MilinkovićDepartment for Medical Biochemistry, Faculty of Pharmacy, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0000-0002-2641-9817
Anđelka MilićInstitute for Orthopedic Surgery "Banjica", 11000 Belgrade, Serbia.
Sanja MirkovićFaculty of Sport and Physical Education, University of Belgrade, 11000 Belgrade, Serbia.
Ankica VujovićClinic for Infectious and Tropical Diseases, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0001-9570-215X
Zoran BaščarevićInstitute for Orthopedic Surgery "Banjica", 11000 Belgrade, Serbia.
Biljana Božić NedeljkovićInstitute of Physiology and Biochemistry "Ivan Djaja", Faculty of Biology, University of Belgrade, 11000 Belgrade, Serbia.

Funding

Ministry of Science, Technological Development and Innovation, Republic of Serbia 451-03-136/2025-03/200161; 451-03-137/2025-03/200161; 451-03-137/2025-03/200178 and 451-03-136/2025-03/200178
6 · The paper itself

Abstract

Osteoarthritis is associated with chronic inflammation, which contributes to a hypercoagulable state. Oxidative stress may further disrupt homeostatic balance, thereby promoting thrombotic events. This study evaluated the association between biomarkers of oxidative stress, inflammation, haemostasis, and bone metabolism in patients with spinal osteoarthritis. A total of 48 patients were included. The levels of inflammatory, bone turnover, haematological, and coagulation biomarkers were determined using standard laboratory methods. Redox status was assessed via prooxidant-antioxidant balance (PAB) and superoxide dismutase (SOD) activity. Patients with elevated PAB showed significantly higher erythrocyte sedimentation rate (ESR) (

Indexed as

coagulationD-dimerosteoarthritisprooxidant-antioxidant balancevitamin D

Identifiers

PMID41752957
PMCPMC12941861

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.