Evidence map›Paper›PMID 41752949›Full record

ArticleLife (Basel, Switzerland)2026

Severe HAPE in a Remote High-Altitude Research Station in Antarctica.

Fanny Larcher, Paul Laforet, Stephane Fraize, Mario Lecca, Riccardo Scipinotti, Gianluca Bianchi Fasani, Salvatore Vagnoni, Sascha Freigang

Abstract readCase Reports
In one paragraph

Article in Life (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Fanny LarcherFrench Polar Institute Paul-Émile Victor (IPEV), 29280 Plouzané, France.
Paul LaforetFrench Polar Institute Paul-Émile Victor (IPEV), 29280 Plouzané, France.
Stephane FraizeFrench Polar Institute Paul-Émile Victor (IPEV), 29280 Plouzané, France.
Mario LeccaProgramma Nazionale di Ricerche in Antartide (PNRA), 00185 Rome, Italy.
Riccardo ScipinottiProgramma Nazionale di Ricerche in Antartide (PNRA), 00185 Rome, Italy.ORCID 0000-0002-0291-7272
Gianluca Bianchi FasaniProgramma Nazionale di Ricerche in Antartide (PNRA), 00185 Rome, Italy.
Salvatore VagnoniProgramma Nazionale di Ricerche in Antartide (PNRA), 00185 Rome, Italy.
Sascha FreigangEuropean Space Agency (ESA), French Polar Institute Paul-Émile Victor (IPEV), Department of Neurosurgery, Medical University Graz, 8010 Graz, Austria.ORCID 0000-0001-8298-1663

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Isolated, confined, and extreme environments hold the opportunity to collect unique biomedical data. These often-remote places present specific medical challenges for deployed expeditioners. Here we report a case of acute severe high altitude pulmonary oedema (HAPE) and its management at a remote research station in Antarctica. At the beginning of the 2023 summer campaign at Concordia Station (3200 m AMSL), a technician presented with shortness of breath and compromised circulation three days after arrival on site. Immediate diagnostics and medical treatments with high-flow oxygen and the use of a mobile hyperbaric chamber after initial resuscitation were administered. Within a time window of 24 h, evacuation to sea level was organised via aircraft (flight duration 4 h, non-pressurised cabin) inside the mobile hyperbaric chamber. The patient was discharged from medical treatment 48 h later in Christchurch (NZ). We conclude that despite rigorous pre-deployment screening, even experienced expeditioners can develop critical medical conditions that require prompt reaction and rescue. Structured assessment tools can aid in their recognition and management.

Indexed as

altitude illnessemergency medicineHAPEhigh altitude pulmonary oedemahyperbaric chamberisolated medicinemountain diseasepolar medicine

Identifiers

PMID41752949
PMCPMC12941443

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.