Evidence map›Paper›PMID 41752857›Full record

ReviewLife (Basel, Switzerland)2026

United Airway Disease: An Evolving Concept? A Scoping Review of the Modern Literature on Integrated Treatment Approaches.

Victor Alexandru, Alexia Manole, Ligia Salomea Groza, Felicia Manole

Abstract readReview
In one paragraph

Review in Life (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Victor AlexandruDoctoral School of Biomedical Sciences, University of Oradea, 410087 Oradea, Romania.ORCID 0009-0002-6584-5840
Alexia ManoleFaculty of Medicine and Pharmacy, University of Oradea, 410087 Oradea, Romania.ORCID 0009-0005-3410-3870
Ligia Salomea GrozaFaculty of Medicine and Pharmacy, University of Oradea, 410087 Oradea, Romania.
Felicia ManoleENT Department, Faculty of Medicine and Pharmacy, University of Oradea, 410087 Oradea, Romania.ORCID 0000-0002-2153-1148

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis scoping review screens modern literature in search of effective treatment approaches that target both upper and lower airway diseases.

methodsAfter the establishment of a research protocol, 227 potential articles were obtained through a logged search method. These were screened and narrowed down to 26 included articles. Data were extracted using a standardized data extraction form and were analyzed thematically and analytically.

resultsThe main integrated treatment approaches are biological (dupilumab was the most mentioned molecule) and non-biological (allergen immunotherapy, nasal saline irrigation, and endoscopic polypectomy). Data suggest that these approaches are effective in improving upper and lower airway outcomes and showcase a good safety profile.

conclusionsPatients with upper and lower airway diseases should benefit from integrated treatment approaches when possible.

Indexed as

allergic rhinitisasthmachronic rhinosinusitis with or without nasal polypstreatment approachesunited airway disease

Identifiers

PMID41752857
PMCPMC12941778

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.