Evidence map›Paper›PMID 41752761›Full record

ArticleMedicina (Kaunas, Lithuania)2026

Amantadine Attenuates Secondary Oxidative and Inflammatory Injury by Modulating the HIF-1α/BNIP3L/HMGB1 Axis in Rat Model of Traumatic Brain Injury.

Ahmet Bindal, Pinar Karabacak, Halil Asci, Ilter Ilhan, Muhammet Yusuf Tepebasi, Orhan Imeci, Ahmet Yunus Hatip, Ozlem Ozmen

Abstract read
In one paragraph

Article in Medicina (Kaunas, Lithuania), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Post-Translational Modifications in Traumatic Brain Injury: Decoding the Proteomic Landscape and Molecular Mechanisms of Secondary Injury.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ahmet BindalDepartment of Anesthesiology and Reanimation, Faculty of Medicine, Suleyman Demirel University, Isparta 32260, Turkey.ORCID 0000-0002-1971-6856
Pinar KarabacakDepartment of Anesthesiology and Reanimation, Faculty of Medicine, Suleyman Demirel University, Isparta 32260, Turkey.
Halil AsciDepartment of Pharmacology, Faculty of Medicine, Suleyman Demirel University, Isparta 32260, Turkey.
Ilter IlhanDepartment of Biochemistry, Faculty of Medicine, Suleyman Demirel University, Isparta 32260, Turkey.ORCID 0000-0003-3739-9580
Muhammet Yusuf TepebasiDepartment of Genetics, Faculty of Medicine, Suleyman Demirel University, Isparta 32260, Turkey.ORCID 0000-0002-1087-4874
Orhan ImeciDepartment of Pharmacology, Faculty of Medicine, Suleyman Demirel University, Isparta 32260, Turkey.ORCID 0000-0002-3850-0137
Ahmet Yunus HatipDepartment of Emergency Medicine, Faculty of Medicine, Suleyman Demirel University, Isparta 32260, Turkey.ORCID 0000-0002-7595-2175
Ozlem OzmenDepartment of Pathology, Faculty of Veterinary Medicine, Burdur Mehmet Akif Ersoy University, Burdur 15030, Turkey.

Funding

Suleyman Demirel University Scientific Research Project Unit TSG-2023-9092
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AmantadineBrain Injuries, TraumaticHMGB1 ProteinHypoxia-Inducible Factor 1, alpha SubunitOxidative StressAnimalsDisease Models, AnimalInflammationMaleMembrane ProteinsNeuroprotective AgentsRatsRats, WistarAmantadineHbp1 protein, ratHif1a protein, ratHMGB1 ProteinHypoxia-Inducible Factor 1, alpha SubunitMembrane ProteinsNeuroprotective Agentscentral nervous systemmitochondrial disordersmitophagyN-methylaspartate antagonistsoxidative stress

Identifiers

PMID41752761
PMCPMC12943473

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.