Evidence map›Paper›PMID 41752460›Full record

ReviewMolecules (Basel, Switzerland)2026

The Potential of Non-Ribosomal Peptide Engineering for Creating New Antimicrobial Complexes.

Evgeniya V Prazdnova, Maxim P Kulikov, Ludmila E Khmelevtsova

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. A MarineMarine drugs · 2026
    Article
  2. Review
  3. Genome Sequence and Antimicrobial Production ofmicroPublication biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Evgeniya V PrazdnovaAcademy of Biology and Medicine Named After D.I. Ivanovskiy, Southern Federal University, Stachki Avenue 194/1, Rostov-on-Don 344090, Russia.ORCID 0000-0001-7823-9044
Maxim P KulikovAcademy of Biology and Medicine Named After D.I. Ivanovskiy, Southern Federal University, Stachki Avenue 194/1, Rostov-on-Don 344090, Russia.ORCID 0000-0002-3792-3445
Ludmila E KhmelevtsovaAcademy of Biology and Medicine Named After D.I. Ivanovskiy, Southern Federal University, Stachki Avenue 194/1, Rostov-on-Don 344090, Russia.ORCID 0000-0003-0781-2207

Funding

Russian Science Foundation 25-66-00009
6 · The paper itself

Abstract

Self-assembling antimicrobial complexes are a promising new technology for the development of antimicrobial, antifungal, and other bioactive agents with targeted delivery, adaptability, and the regulation of processes over time. Ribosomally synthesized antimicrobial peptides (AMPs) are most frequently considered as the basis for such complexes; however, we suggest that non-ribosomally synthesized peptides (NRPs) should be considered as molecules that also hold potential for engineering and already possess a set of qualities that AMPs are still to be engineered to have. This review examines the key features of NRP structure and self-assembly that determine their potential as antimicrobial agents, as well as NRP engineering methods through which new, more advanced agents for combating antibiotic-resistant microorganisms can be created.

Indexed as

Anti-Infective AgentsAntimicrobial PeptidesProtein EngineeringHumansAnti-Infective AgentsAntimicrobial Peptidesantibiotic resistanceantimicrobial peptideslipopeptidesnanostructuresnon-ribosomal peptidesNRPS engineeringself-assembly

Identifiers

PMID41752460
PMCPMC12943608

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.