Evidence map›Paper›PMID 41752422›Full record

ReviewMolecules (Basel, Switzerland)2026

Valorization of Plant-Based Food By-Products Through Green Extraction of Bioactive Compounds for Functional Food.

Cristina-Anca Danciu, Alina-Georgeta Mag, Cristian Stanciu, Livia Vidu, Mirela Stanciu

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Feature Reviews on Food Microbiology.Foods (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Cristina-Anca DanciuFaculty of Agricultural Sciences, Food Industry and Environmental Protection, Lucian Blaga University of Sibiu, 7-9 Dr. Ion Ratiu Str., 550012 Sibiu, Romania.ORCID 0000-0002-3739-0810
Alina-Georgeta MagFaculty of Social Sciences and Humanities, Lucian Blaga University of Sibiu, 5-7 Victoriei Blvd., 550024 Sibiu, Romania.ORCID 0000-0002-0807-3963
Cristian StanciuFaculty of Sciences, Lucian Blaga University of Sibiu, 5-7 Dr. Ion Rațiu Street, 550012 Sibiu, Romania.
Livia ViduFaculty of Animal Productions Engineering and Management, University of Agronomic Sciences and Veterinary Medicine of Bucharest, 59 Marasti Blvd., District 1, 011464 Bucharest, Romania.ORCID 0000-0003-4530-8503
Mirela StanciuFaculty of Agricultural Sciences, Food Industry and Environmental Protection, Lucian Blaga University of Sibiu, 7-9 Dr. Ion Ratiu Str., 550012 Sibiu, Romania.ORCID 0000-0002-9797-376X

Funding

Lucian Blaga University of Sibiu LBUS-IRG-2023-09
6 · The paper itself

Abstract

The revalorization of food processing by-products represents a critical strategy for enhancing resource efficiency and advancing circularity within the food system. This review examines the potential of three major plant-based agro-industrial by-products-fruit and vegetable residues, brewer's spent grain, and spent coffee grounds-as sources of high-value functional ingredients. These by-products contain bioactive compounds, including dietary fibers, polyphenols, proteins, peptides, oils, and antioxidants, that can be recovered using emerging green extraction and bioprocessing technologies. Conventional extraction methods are progressively being replaced or hybridized with enzyme-assisted, ultrasound-assisted, microwave-assisted, and deep eutectic solvent techniques to improve yield, reduce solvent consumption, and preserve bioactivity. The recovered compounds have demonstrated promising applications as gelling agents (pectin), natural colorants and antioxidants, protein-enriched flours, prebiotic fibers, and bioactive extracts for functional food and nutraceutical formulations. However, challenges persist in standardizing feedstock composition, scaling continuous extraction processes, ensuring safety and regulatory compliance, and generating robust techno-economic and life-cycle assessments to validate sustainability claims. This review synthesizes biochemical composition data, processing pathways, food applications, and regulatory considerations, and identifies research priorities for developing integrated, scalable biorefinery models that valorize food by-products into market-ready functional ingredients.

Indexed as

Functional FoodGreen Chemistry TechnologyPhytochemicalsPlant ExtractsPlantsAntioxidantsFood Loss and WasteFruitAntioxidantsFood Loss and WastePhytochemicalsPlant Extractsbioactive compoundsfunctional ingredientsgreen extraction technologiesplant-based food by-productsvalorization

Identifiers

PMID41752422
PMCPMC12943265

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.