In one paragraphArticle in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
9 authors.
Geovane Dias-LopesDepartamento de Ciências Biomédicas e Saúde, Instituto de Biologia Roberto Alcântara Gomes, Universidade do Estado do Rio de Janeiro, Rua Arízio Gomes da Costa 186-Jardim Flamboyant, Cabo Frio 28905-320, RJ, Brazil.ORCID 0000-0003-4448-1398 Luana Ribeiro Dos AnjosLaboratório de Química Orgânica Fina, Departamento de Química e Bioquímica, Escola de Ciências e Tecnologia, Universidade Estadual Paulista, Rua Roberto Simonsen, 305-Centro Educacional, Presidente Prudente 19060-080, SP, Brazil.ORCID 0000-0002-2487-6176 Sara Maria Xavier da CruzLaboratório de Biologia Molecular e Doenças Endêmicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Avenida Brazil 4365-Manguinhos, Rio de Janeiro 21040-900, RJ, Brazil.ORCID 0009-0004-2230-1338 Cauã Dias AbrãoLaboratório de Química Orgânica Fina, Departamento de Química e Bioquímica, Escola de Ciências e Tecnologia, Universidade Estadual Paulista, Rua Roberto Simonsen, 305-Centro Educacional, Presidente Prudente 19060-080, SP, Brazil.ORCID 0009-0000-7817-6338 Maria Eduarda Pinto GonçalvesLaboratório de Biologia Molecular e Doenças Endêmicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Avenida Brazil 4365-Manguinhos, Rio de Janeiro 21040-900, RJ, Brazil.
Franklin Souza-SilvaCentro de Desenvolvimento Tecnológico em Saúde, Fundação Oswaldo Cruz, Avenida Brazil, 4365-Manguinhos, Rio de Janeiro 21040-900, RJ, Brazil.ORCID 0000-0002-9216-4306 Anna FabisikovaMass Spectrometry Centre, Faculty of Chemistry, University of Vienna, Währinger Straße 38, A-1090 Vienna, Austria.
Eduardo Rene Perez GonzálezLaboratório de Química Orgânica Fina, Departamento de Química e Bioquímica, Escola de Ciências e Tecnologia, Universidade Estadual Paulista, Rua Roberto Simonsen, 305-Centro Educacional, Presidente Prudente 19060-080, SP, Brazil.ORCID 0000-0003-1348-8554 Carlos Roberto AlvesLaboratório de Biologia Molecular e Doenças Endêmicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Avenida Brazil 4365-Manguinhos, Rio de Janeiro 21040-900, RJ, Brazil.ORCID 0000-0001-8703-426X Funding
Coordenação de Aperfeicoamento de Pessoal de Nível Superior Finance Code 001Fundação de Amparo à Pesquisa do Estado de São Paulo 2021/02595-8Fundação de Amparo à Pesquisa do Estado de São Paulo 2025/01056-7Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/010.000983/2019Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/203.931/2024Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/210.712/2025National Council for Scientific and Technological Development 305287/2023-0National Council for Scientific and Technological Development 441634/2024-9
6 · The paper itselfAbstract
Leishmaniasis remains an important neglected tropical disease, and current treatments are limited by toxicity, resistance, and low bioavailability. In this study, novel guanidine derivatives were evaluated through an integrated approach, combining in silico physicochemical profiling with in vitro biological assays using
Indexed as
Antiprotozoal AgentsGuanidineLeishmania braziliensisAnimalsMacrophagesMiceMolecular StructureAntiprotozoal AgentsGuanidinechemotherapydrug screeningguanidinesLeishmania (Viannia) braziliensis
Identifiers
PMID41752407
PMCPMC12943680
What OpenQuestion holds
Textmetadata
LicenceCC BY
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