ArticleMolecules (Basel, Switzerland)2026
Beyond α-Glucosidase and α-Amylase Inhibition: Integrated In Vitro and Multi-Scale In Silico Insights into the Antidiabetic and Antioxidant Mechanisms of
Thi-Van-Anh Nguyen, Duong Quang Quy, Nguyen Thanh Tung, Nguyen Thu Huyen, Pham Le Minh, Nguyen T Minh Huyen, Tue-Tam Ho, Nguyen Thi Thu Ha, Gerardo M Casanola-Martin, Bakhtiyor Rasulev and 1 more
Abstract read
In one paragraphArticle in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
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2 · The registryThe trial behind it
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5 · Who and what moneyAuthors and funding
11 authors.
Thi-Van-Anh NguyenDepartment of Life Sciences, University of Science and Technology of Hanoi (USTH), Vietnam Academy of Science and Technology, 18-Hoang Quoc Viet, Nghia Do, Hanoi 10000, Vietnam.
Duong Quang QuyDepartment of Life Sciences, University of Science and Technology of Hanoi (USTH), Vietnam Academy of Science and Technology, 18-Hoang Quoc Viet, Nghia Do, Hanoi 10000, Vietnam.ORCID 0009-0007-6215-678X Nguyen Thanh TungDepartment of Pharmacognosy, Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Cua Nam, Hanoi 10000, Vietnam.ORCID 0000-0002-5740-7392 Nguyen Thu HuyenDepartment of Life Sciences, University of Science and Technology of Hanoi (USTH), Vietnam Academy of Science and Technology, 18-Hoang Quoc Viet, Nghia Do, Hanoi 10000, Vietnam.
Pham Le MinhDepartment of Life Sciences, University of Science and Technology of Hanoi (USTH), Vietnam Academy of Science and Technology, 18-Hoang Quoc Viet, Nghia Do, Hanoi 10000, Vietnam.
Nguyen T Minh HuyenDepartment of Life Sciences, University of Science and Technology of Hanoi (USTH), Vietnam Academy of Science and Technology, 18-Hoang Quoc Viet, Nghia Do, Hanoi 10000, Vietnam.ORCID 0000-0002-5942-9659 Tue-Tam HoDepartment of Pharmacognosy, Hanoi University of Pharmacy, 13-15 Le Thanh Tong, Cua Nam, Hanoi 10000, Vietnam.
Nguyen Thi Thu HaInstitute of Chemistry (ICH), Vietnam Academy of Science and Technology, 18-Hoang Quoc Viet, Nghia Do, Hanoi 10000, Vietnam.
Gerardo M Casanola-MartinDepartment of Coatings and Polymeric Materials, North Dakota State University, Fargo, ND 58102, USA.ORCID 0000-0003-0383-2032 Bakhtiyor RasulevDepartment of Coatings and Polymeric Materials, North Dakota State University, Fargo, ND 58102, USA.ORCID 0000-0002-7845-4884 Hai Pham-TheDepartment of Life Sciences, University of Science and Technology of Hanoi (USTH), Vietnam Academy of Science and Technology, 18-Hoang Quoc Viet, Nghia Do, Hanoi 10000, Vietnam.ORCID 0000-0003-4531-7223 Funding
USTH USTH.LS.01/24-25
6 · The paper itselfAbstract
Diabetes mellitus is a major global health concern associated with severe metabolic and cardiovascular complications. This study evaluated the antidiabetic and antioxidant activities of
Indexed as
alpha-Amylasesalpha-GlucosidasesAntioxidantsGlycoside Hydrolase InhibitorsHypoglycemic AgentsPlant Components, AerialPlant ExtractsComputer SimulationMolecular Docking SimulationMolecular Dynamics Simulationalpha-Amylasesalpha-GlucosidasesAntioxidantsGlycoside Hydrolase InhibitorsHypoglycemic AgentsPlant Extractsantidiabetic and antioxidant activityin vitro testsmolecular simulationO. Corniculata aerial extractpolypharmacological networkquantum chemistry
Identifiers
PMID41752406
PMCPMC12942679
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