Evidence map›Paper›PMID 41752388›Full record

ReviewMolecules (Basel, Switzerland)2026

Strategies for Metabolic Engineering of

Jiali Liu, Yilin Shi, Daxin Zhao, Minghao Lin, Ping Wang, Ying Zhou, Xiaohui Yan

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jiali LiuNational Key Laboratory of Chinese Medicine Modernization, State Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Tianjin 301617, China.ORCID 0009-0002-8957-8927
Yilin ShiNational Key Laboratory of Chinese Medicine Modernization, State Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Tianjin 301617, China.
Daxin ZhaoNational Key Laboratory of Chinese Medicine Modernization, State Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Tianjin 301617, China.
Minghao LinSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Tianjin 301617, China.
Ping WangSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Tianjin 301617, China.
Ying ZhouSchool of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Tianjin 301617, China.
Xiaohui YanNational Key Laboratory of Chinese Medicine Modernization, State Key Laboratory of Component-Based Chinese Medicine, Tianjin University of Traditional Chinese Medicine, 10 Poyanghu Road, Tianjin 301617, China.ORCID 0000-0001-7295-8902

Funding

National Key R&D Program of China 2020YFA0907900Technology Project of Haihe Laboratory of Modern Chinese Medicine 25HHZYSS00024
6 · The paper itself

Abstract

β-Carotene has extensive applications in the food, pharmaceutical, and cosmetics industries. Traditional chemical synthesis methods face challenges such as byproduct residues and high costs, whereas natural extraction is constrained by low yields and complex processes. Recent advancements in synthetic biology and metabolic engineering have paved the way for the heterologous biosynthesis of β-carotene in microorganisms. Owing to its rapid growth, convenience of genetic manipulation, and suitability for producing apocarotenoids,

Indexed as

beta CaroteneEscherichia coliMetabolic EngineeringBiosynthetic PathwaysFermentationMetabolic Networks and Pathwaysbeta CaroteneE. coliMEP pathwaymetabolic engineeringMVA pathwayβ-carotene

Identifiers

PMID41752388
PMCPMC12943421

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.