In one paragraphArticle in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
9 authors.
Sonia PanicoInstitute of Genetics and Biophysics 'Adriano Buzzati-Traverso'-CNR, Angiogenesis LAB, 80131 Naples, Italy.ORCID 0000-0002-8290-6521 Antonio AdinolfiInstitute of Genetics and Biophysics 'Adriano Buzzati-Traverso'-CNR, Angiogenesis LAB, 80131 Naples, Italy.
Sara Magliacane TrottaInstitute of Genetics and Biophysics 'Adriano Buzzati-Traverso'-CNR, Angiogenesis LAB, 80131 Naples, Italy.ORCID 0009-0003-9400-3279 Luca D'OrsiInstitute of Genetics and Biophysics 'Adriano Buzzati-Traverso'-CNR, Angiogenesis LAB, 80131 Naples, Italy.
Grazia MercadanteInstitute of Genetics and Biophysics 'Adriano Buzzati-Traverso'-CNR, Angiogenesis LAB, 80131 Naples, Italy.
Andrea ParadisiApoptosis, Cancer and Development Laboratory-Equipe labellisée 'La Ligue', LabEx DEVweCAN, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Centre Léon Bérard, 69008 Lyon, France.ORCID 0000-0003-2218-3859 Patrick MehlenApoptosis, Cancer and Development Laboratory-Equipe labellisée 'La Ligue', LabEx DEVweCAN, Centre de Recherche en Cancérologie de Lyon, INSERM U1052-CNRS UMR5286, Université de Lyon, Centre Léon Bérard, 69008 Lyon, France.
Valeria TaralloInstitute of Genetics and Biophysics 'Adriano Buzzati-Traverso'-CNR, Angiogenesis LAB, 80131 Naples, Italy.ORCID 0000-0002-6920-4402 Sandro De FalcoInstitute of Genetics and Biophysics 'Adriano Buzzati-Traverso'-CNR, Angiogenesis LAB, 80131 Naples, Italy.ORCID 0000-0002-6501-1697 Funding
Consiglio Nazionale delle Ricerche Italy FOE-2021 DBA.AD005.225Consiglio Nazionale delle Ricerche Italy FOE-2022 DSB.AD006.371.001Italian Ministry of University and Research PRIN PNRR P2022C9HJYNext Generation EU - Italian Ministry of University and Research PNRR "National Center for Gene Therapy and Drugs based on RNA Technology" CN00000041
6 · The paper itselfAbstract
Prolyl 3-hydroxylase 2 (P3H2) is a key enzyme involved in the architecture of the extracellular matrix (ECM). While previously shown to be regulated by VEGF-A and to play a role in angiogenesis, its function in cancer remains ambiguous. While characterized as a tumor suppressor, its precise function in colorectal cancer (CRC) progression is poorly defined. Bioinformatic analysis and patient data reveal that
Indexed as
Colorectal NeoplasmsNeovascularization, PathologicProcollagen-Proline DioxygenaseAnimalsCell Line, TumorCell ProliferationCollagen Type IVDisease ProgressionExtracellular MatrixFemaleGene Expression Regulation, NeoplasticHCT116 CellsHumansMiceMice, NudeNeoplasm MetastasisCollagen Type IVProcollagen-Proline DioxygenaseVascular Endothelial Growth Factor Aangiogenesiscolorectal cancerProlyl 3-hydroxylase 2
Identifiers
PMID41752135
PMCPMC12941085
What OpenQuestion holds
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