Evidence map›Paper›PMID 41752110›Full record

ArticleInternational journal of molecular sciences2026

Smaller Oxygen Nanobubbles More Effectively Suppress Colitis and Colon Carcinogenesis than Larger Oxygen Nanobubbles.

Gendensuren Dorjkhorloo, Haruka Okami, Nobutoshi Mutsuki, Navchaa Gombodorj, Bilguun Erkhem-Ochir, Enkhtuvshin Khorolgarav, Seyed Mostafa Mostafavi Zadeh, Chika Katayama, Eri Miyata, Yuta Shibasaki and 11 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Gendensuren DorjkhorlooDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi 371-8510, Japan.
Haruka OkamiDivision of Gene Therapy Science, Initiative for Advanced Research (GIAR), Gunma University, 3-39-22 Showamachi, Maebashi 371-8511, Japan.ORCID 0009-0003-8962-0950
Nobutoshi MutsukiSigma Technology Inc., 1-11-29 Sotono, Hitachinaka 312-0053, Japan.
Navchaa GombodorjDivision of Gene Therapy Science, Initiative for Advanced Research (GIAR), Gunma University, 3-39-22 Showamachi, Maebashi 371-8511, Japan.
Bilguun Erkhem-OchirDivision of Gene Therapy Science, Initiative for Advanced Research (GIAR), Gunma University, 3-39-22 Showamachi, Maebashi 371-8511, Japan.
Enkhtuvshin KhorolgaravDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi 371-8510, Japan.
Seyed Mostafa Mostafavi ZadehDivision of Gene Therapy Science, Initiative for Advanced Research (GIAR), Gunma University, 3-39-22 Showamachi, Maebashi 371-8511, Japan.
Chika KatayamaDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi 371-8510, Japan.ORCID 0000-0003-4790-1490
Eri MiyataDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi 371-8510, Japan.
Yuta ShibasakiDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi 371-8510, Japan.
Nobuhiro NakazawaDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi 371-8510, Japan.ORCID 0000-0001-8705-2150
Chika KomineDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi 371-8510, Japan.
Takuya ShiraishiDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi 371-8510, Japan.
Takuhisa OkadaDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi 371-8510, Japan.
Akiharu KimuraDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi 371-8510, Japan.ORCID 0000-0002-6832-4146
Akihiko SanoDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi 371-8510, Japan.
Makoto SakaiDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi 371-8510, Japan.ORCID 0000-0003-0860-3132
Ken ShirabeDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi 371-8510, Japan.
Hiroshi SaekiDepartment of General Surgical Science, Graduate School of Medicine, Gunma University, 3-39-22 Showamachi, Maebashi 371-8510, Japan.
Dai YamanouchiDepartment of Vascular Surgery, Fujita Health University, Toyoake 470-1192, Japan.ORCID 0000-0002-5720-3939
Takehiko YokoboriDivision of Gene Therapy Science, Initiative for Advanced Research (GIAR), Gunma University, 3-39-22 Showamachi, Maebashi 371-8511, Japan.ORCID 0000-0003-3284-4796

Funding

Japan Society for the Promotion of Science 23K08106Japan Society for the Promotion of Science 24K11883Japan Society for the Promotion of Science 24K23504Japan Society for the Promotion of Science 25K11948
6 · The paper itself

Abstract

Oxygen nanobubble (NBO

Indexed as

ColitisColonic NeoplasmsOxygenAnimalsAzoxymethaneCarcinogenesisColitis-Associated NeoplasmsDextran SulfateDisease Models, AnimalHypoxia-Inducible Factor 1, alpha SubunitMaleMiceMice, Inbred C57BLParticle SizeAzoxymethaneDextran SulfateHypoxia-Inducible Factor 1, alpha SubunitOxygenAOM/DSS mouse modelcolitis-associated cancerHIF-1αhypoxiananobubble size

Identifiers

PMID41752110
PMCPMC12940223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.