Evidence map›Paper›PMID 41752090›Full record

ArticleInternational journal of molecular sciences2026

Usnic Acid Derivatives as Inhibitors of

Aleksandr S Filimonov, Maria V Zateeva, Grigory V Mechetin, Olga A Luzina, Chatchakorn Eurtivong, Suat Sari, Anton V Endutkin, Jóhannes Reynisson, Konstantin P Volcho, Nariman F Salakhutdinov and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Aleksandr S FilimonovN. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 9 Lavrentieva Ave., Novosibirsk 630090, Russia.ORCID 0000-0003-2798-2844
Maria V ZateevaInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 8 Lavrentieva Ave., Novosibirsk 630090, Russia.ORCID 0000-0001-5619-2708
Grigory V MechetinInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 8 Lavrentieva Ave., Novosibirsk 630090, Russia.ORCID 0000-0002-8643-8075
Olga A LuzinaN. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 9 Lavrentieva Ave., Novosibirsk 630090, Russia.ORCID 0000-0001-8627-3453
Chatchakorn EurtivongDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Mahidol University, Bangkok 10400, Thailand.ORCID 0000-0002-4501-5113
Suat SariDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Hacettepe University, Ankara 06100, Turkey.ORCID 0000-0002-8248-4218
Anton V EndutkinInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 8 Lavrentieva Ave., Novosibirsk 630090, Russia.ORCID 0000-0002-3647-6591
Jóhannes ReynissonSchool of Pharmacy, Keele University, Hornbeam Building, Staffordshire ST5 5BG, UK.ORCID 0000-0003-4174-9512
Konstantin P VolchoN. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 9 Lavrentieva Ave., Novosibirsk 630090, Russia.ORCID 0000-0002-4083-9324
Nariman F SalakhutdinovN. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, 9 Lavrentieva Ave., Novosibirsk 630090, Russia.
Dmitry O ZharkovInstitute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, 8 Lavrentieva Ave., Novosibirsk 630090, Russia.

Funding

Russian Science Foundation 21-64-00017p
6 · The paper itself

Abstract

Tuberculosis (TB) remains a global health issue exacerbated by spreading drug resistance and lengthy treatment regimens. Targeting bacterial DNA-repair pathways, particularly those counteracting host-generated genotoxic stress, represents a promising strategy to sensitize

Indexed as

Antitubercular AgentsBacterial ProteinsBenzofuransEnzyme InhibitorsMycobacterium tuberculosisUracil-DNA GlycosidaseCatalytic DomainDNA RepairHumansMolecular Docking SimulationAntitubercular AgentsBacterial ProteinsBenzofuransEnzyme InhibitorsUracil-DNA Glycosidaseusnic acidDNA glycosylasesDNA repairinhibitorsMycobacterium tuberculosisuracil–DNA glycosylaseusnic acidvirtual screening

Identifiers

PMID41752090
PMCPMC12941137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.