Evidence map›Paper›PMID 41751912›Full record

SynthesisInternational journal of molecular sciences2026

Global Microbiome: Core and Unique Signatures Across Diverse Populations.

Sherri Huang, Diptaraj S Chaudhari, Rohit Shukla, Pushti Kanani, Rola S Zeidan, Yi Lin, Wesley Burrow, Robert T Mankowski, Shalini Jain, Hariom Yadav

Abstract readMeta-Analysis
In one paragraph

Synthesis in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sherri HuangKaiser Permanente San Leandro Medical Center, San Leandro, CA 94577, USA.
Diptaraj S ChaudhariDepartment of Physiology, Wayne State University School of Medicine, Detroit, MI 48301, USA.ORCID 0000-0001-9236-7683
Rohit ShuklaUSF Center for Microbiome Research, Microbiomes Institute, Tampa, FL 33612, USA.ORCID 0000-0002-0759-8362
Pushti KananiUSF Center for Microbiome Research, Microbiomes Institute, Tampa, FL 33612, USA.
Rola S ZeidanDepartment of Physiology and Aging, College of Medicine, University of Florida, Gainesville, FL 32610, USA.ORCID 0009-0000-0838-0122
Yi LinDepartment of Physiology and Aging, College of Medicine, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0002-8794-8886
Wesley BurrowDr. Kiran C. Patel College of Allopathic Medicine, Nova Southeastern University, Fort Lauderdale, FL 33328, USA.
Robert T MankowskiDivision of Gerontology, Geriatrics and Palliative Care, Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294, USA.
Shalini JainUSF Center for Microbiome Research, Microbiomes Institute, Tampa, FL 33612, USA.
Hariom YadavUSF Center for Microbiome Research, Microbiomes Institute, Tampa, FL 33612, USA.ORCID 0000-0003-4504-1597

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Earlier analyses evaluating patterns of gut microbiota in individuals from different geographies and age groups are heterogeneous in methodology, precluding broader conclusions about the relationship between the gut microbiome and geographic region, age, and clinical health. Here, we systematically conducted a meta-analysis of 16s rRNA gut microbiome sequencing data representing 10,878 samples across North America, Europe, Africa, Asia and Oceania. Our analysis included 27 countries and three age groups (neonate to age 17, or AG01; ages 18 to 64, or AG02; 65 and above, or AG03). We identified that Firmicutes, Bacteriodetes, and Proteobacteria constitute core phyla across geographic regions. A differing predominance of top families alongside core family

Indexed as

BacteriaGastrointestinal MicrobiomeAdolescentEuropeHumansNorth AmericaRNA, Ribosomal, 16SRNA, Ribosomal, 16Sagingcoreenterotypeglobalmicrobiomeuniqueworld

Identifiers

PMID41751912
PMCPMC12940378

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.