Evidence map›Paper›PMID 41751896›Full record

ReviewInternational journal of molecular sciences2026

Adipose-Tissue Macrophage Diversity and Functions.

Sacha Grenet, Stoyan Ivanov, Giulia Chinetti

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Sacha GrenetFaculté de Médecine, Université Côte d'Azur, CNRS, LP2M, 28, Avenue de Valombrose, 06107 Nice, Cedex 2, France.ORCID 0009-0000-4028-8895
Stoyan IvanovFaculté de Médecine, Université Côte d'Azur, CNRS, LP2M, 28, Avenue de Valombrose, 06107 Nice, Cedex 2, France.
Giulia ChinettiFaculté de Médecine, Université Côte d'Azur, CNRS, LP2M, 28, Avenue de Valombrose, 06107 Nice, Cedex 2, France.ORCID 0000-0001-8048-8138

Funding

Agence Nationale de la Recherche NA
6 · The paper itself

Abstract

Macrophages are the predominant immune cell type found in adipose tissue (AT). They play a critical role in tissue homeostasis and participate in metabolic regulation. In white adipose tissue (WAT), studies show that multiple macrophage subsets co-exist in the very same microenvironment. Yet these cells express selective membrane markers, allowing for identifying several well-distinguished populations. In the present review we discuss the diversity and functions of white-adipose-tissue macrophages. We summarize current knowledge regarding the intratissue distribution of macrophage populations and their specific association with stromal cells and discuss the mechanisms governing adipose-tissue macrophage generation and survival. We emphasize the central role of adipose-tissue macrophages in handling local lipid levels. A particular focus is placed on the recently described population of lipid-associated macrophages (LAMs), particularly abundant in adipose tissue during obesity development.

Indexed as

Adipose TissueAdipose Tissue, WhiteMacrophagesAnimalsHumansLipid MetabolismObesityimmune cellsinflammationmacrophagesobesity

Identifiers

PMID41751896
PMCPMC12941317

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.