Evidence map›Paper›PMID 41751882›Full record

ArticleInternational journal of molecular sciences2026

Yun-Jhu Hou, Chien-Yun Hsiang, Hsin-Yi Lo, Fang-Chia Chang, Tin-Yun Ho

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yun-Jhu HouDepartment of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, Taipei 106319, Taiwan.
Chien-Yun HsiangDepartment of Microbiology and Immunology, China Medical University, Taichung 404328, Taiwan.ORCID 0000-0002-6507-8015
Hsin-Yi LoSchool of Chinese Medicine & Graduate Institute of Chinese Medicine, China Medical University, Taichung 404328, Taiwan.
Fang-Chia ChangGraduate Institute of Veterinary Medicine, National Taiwan University, Taipei 106319, Taiwan.ORCID 0000-0003-0271-5416
Tin-Yun HoSchool of Chinese Medicine & Graduate Institute of Chinese Medicine, China Medical University, Taichung 404328, Taiwan.ORCID 0000-0003-2390-1461

Funding

National Science and Technology Council NSTC114-2320-B-039-035-MY3National Science and Technology Council NSTC114-2320-B-039-036-MY3
6 · The paper itself

Abstract

Chronic inflammation-driven colorectal cancer (CRC) is critically mediated by interleukin-17A (IL-17A)-dependent immune responses and nuclear factor-κB (NF-κB) signaling, which promote immune cell infiltration and tumor progression. In this study, the anti-tumor efficacy and molecular mechanisms of a standardized extract of

Indexed as

ColitisColitis-Associated NeoplasmsColorectal NeoplasmsHedyotisInterleukin-17NF-kappa BPlant ExtractsReceptors, Interleukin-17Signal TransductionAnimalsCoumaric AcidsHumansMaleMiceMice, Inbred C57BLMolecular Docking SimulationCoumaric Acidsferulic acidIl17ra protein, mouseInterleukin-17NF-kappa BPlant ExtractsReceptors, Interleukin-17colorectal cancerferulic acidHedyotis diffusainterleukin-17Anuclear factor-κB

Identifiers

PMID41751882
PMCPMC12941307

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.