Differential Gene Expression in Differentiated Human Neuroblastoma SH-SY5Y Cells in Response to a Cocktail of Monoamine Oxidase Inhibitors.

Prakshit Niraula, Rachel A Page, Barry R Palmer, Penelope Truman

Abstract read

In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Prakshit NiraulaSchool of Health Sciences, Massey University, Wellington 6021, New Zealand.

Rachel A PageSchool of Health Sciences, Massey University, Wellington 6021, New Zealand.ORCID 0000-0002-5971-4097

Barry R PalmerSchool of Health Sciences, Massey University, Wellington 6021, New Zealand.ORCID 0000-0003-0741-5033

Penelope TrumanSchool of Health Sciences, Massey University, Wellington 6021, New Zealand.ORCID 0000-0003-1417-1313

Funding

Health Research Council of New Zealand HRC 17/655Massey University PhD scholarship P. NiraulaMassey University Research Fund B Palmer

6 · The paper itself

Abstract

Differentiated human neuroblastoma (SH-SY5Y) cells were exposed to either 0.2 μM nicotine, a tobacco smoke preparation (TPM) diluted to the same nicotine concentration, or a cocktail of seven tobacco smoke monoamine oxidase inhibitors (MAOIs) at the concentrations measured in the TPM. Treatment occurred for 3 days, such that the cellular monoamine oxidase (MAO) concentration was reduced by approximately 50% in both the TPM and MAOI cocktail exposure groups. Changes in

Indexed as

Cell DifferentiationGene Expression Regulation, NeoplasticMonoamine OxidaseMonoamine Oxidase InhibitorsNeuroblastomaCell Line, TumorGene Expression ProfilingHumansNicotineMonoamine OxidaseMonoamine Oxidase InhibitorsNicotineglobal gene expressionmonoamine oxidase inhibitorsnicotineqPCRtobacco dependencetobacco particulate matter

Identifiers

PMID41751825

DOI10.3390/ijms27041689

PMCPMC12940261

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.