Evidence map›Paper›PMID 41751759›Full record

ReviewInternational journal of molecular sciences2026

Microbiome, Epigenetics, and Nutritional Factors in Shaping Perinatal Pregnancy Outcomes.

Miljana Z Jovandaric, Sandra Babic, Milos Milincic, Biljana Medjo, Misela Raus, Mirjana Krstic, Dejan Tiric

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Review
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  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Miljana Z JovandaricDepartment of Neonatology, Clinic for Gynecology and Obstetrics, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0003-0294-6353
Sandra BabicDepartment of Obstetrics and Gynecology, Clinic for Gynecology and Obstetrics, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0002-4003-0576
Milos MilincicDepartment of Obstetrics and Gynecology, Clinic for Gynecology and Obstetrics, University Clinical Center of Serbia, 11000 Belgrade, Serbia.ORCID 0000-0002-1822-0314
Biljana MedjoPediatric and Neonatal Intensive Care Unit, University Children's Hospital, 11000 Belgrade, Serbia.ORCID 0000-0003-0060-427X
Misela RausFaculty of Medicine, University of Belgrade, 11000 Belgrade, Serbia.ORCID 0009-0002-4762-9175
Mirjana KrsticHospital for Gynecology and Obstetrics, Clinical Hospital Center Zemun, 11080 Zemun, Serbia.
Dejan TiricDepartment of Obstetrics and Gynecology, University Clinical Hospital Mostar, 88000 Mostar, Bosnia and Herzegovina.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maternal nutrition and gut microbiome composition are central regulators of fetal development and perinatal outcomes, modulating immune signaling, oxidative balance, and epigenetic programming. The authors searched PubMed, Scopus, the Cochrane Library, and Web of Science for full-text, peer-reviewed articles published in English between 2010 and 2025, using keywords relevant to maternal diet, gut microbiome, epigenetic modifications, oxidative stress, reactive oxygen species (ROS), short-chain fatty acids (SCFAs), placental function, and perinatal outcomes. Selected studies provided detailed insights into how maternal dietary patterns and microbiome-derived metabolites influence placental function, fetal growth, and neonatal health. Integration of the microbiome, epigenetics, and nutritional factors reveals key molecular and metabolic networks that shape perinatal health. Targeted modulation of these networks provides a foundation for personalized strategies to improve neonatal outcomes.

Indexed as

Epigenesis, GeneticGastrointestinal MicrobiomeMaternal Nutritional Physiological PhenomenaPregnancy OutcomeAnimalsDevelopmental Origins of Health and DiseaseFemaleFetal DevelopmentHumansOxidative StressPregnancyepigeneticmicrobiomenutritionoxidative stressperinatal outcome

Identifiers

PMID41751759
PMCPMC12941002

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.