Evidence map›Paper›PMID 41751694›Full record

ArticleEntropy (Basel, Switzerland)2026

Dynamic Exploration of Resting-State Brain Attractors Altered in Major Depressive Disorder.

Leonor Abreu, Joana Cabral

Abstract read
In one paragraph

Article in Entropy (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Leonor AbreuInstitute for Systems and Robotics (ISR-Lisboa), Instituto Superior Técnico, University of Lisbon, 1049-001 Lisboa, Portugal.
Joana CabralInstitute for Systems and Robotics (ISR-Lisboa), Instituto Superior Técnico, University of Lisbon, 1049-001 Lisboa, Portugal.ORCID 0000-0002-6715-0826

Funding

LARSyS funding from the Portuguese Foundation for Science and Tecnhology FCT (DOI: 10.54499/LA/P/0083/2020, 10.54499) DOI: 10.54499/LA/P/0083/2020, 10.54499
6 · The paper itself

Abstract

Major depressive disorder (MDD) represents a heterogeneous condition lacking reliable neurobiological biomarkers and a mechanistic understanding. Time-resolved characterization of brain dynamics reveals that mental health is associated with a characteristic dynamical regime, exhibiting spontaneous switching between a repertoire of ghost attractor states forming resting-state networks. Analysing resting-state fMRI data from 848 patients with MDD and 794 healthy controls across 17 sites in China (REST-meta-MDD) using Leading Eigenvector Dynamics Analysis (LEiDA), we found patients with MDD exhibited significantly reduced default mode network (DMN) occupancy (

Indexed as

brain dynamicsLEiDAmajor depressive disorderresting-state networks

Identifiers

PMID41751694
PMCPMC12939193

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.