Evidence map›Paper›PMID 41751279›Full record

ArticleBiomedicines2026

Phospholipid-Based Delivery System Optimizes the Solubility and Systemic Exposure of Palmitoylethanolamide and Supports Clinical Benefits in Chronic Neuropathic Low Back Pain.

Amjad Khan, Fazle Rabbani, Ayesha Kanwal, Areaba Shafiq, Ikram Ujjan, Anna Vellaccio, Massimo Ronchi, Giovanna Petrangolini, Eric De Combarieu, Silvia Turroni and 1 more

Abstract read
In one paragraph

Article in Biomedicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Palmitoylethanolamide in Human and Animal Obesity.Molecules (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Frontiers in molecular biosciences · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Amjad KhanNuffield Division of Clinical Laboratory Sciences (NDCLS), Radcliffe Department of Medicine, University of Oxford, John Radcliffe Hospital, Headley Way, Oxford OX3 9DU, UK.
Fazle RabbaniDepartment of Psychiatry, Lady Reading Hospital (LRH)-MTI, Peshawar 25000, Pakistan.
Ayesha KanwalDepartment of Psychiatry, Lady Reading Hospital (LRH)-MTI, Peshawar 25000, Pakistan.ORCID 0009-0004-7484-035X
Areaba ShafiqDepartment of Psychiatry, Lady Reading Hospital (LRH)-MTI, Peshawar 25000, Pakistan.ORCID 0009-0007-5562-2623
Ikram UjjanDepartment of Pathology, Liaquat University of Medical & Health Sciences, Jamshoro 76090, Pakistan.ORCID 0000-0002-9032-4353
Anna VellaccioMedical, Formulation Development and R&D Departments, Indena, S.p.A, Viale Ortles, 12, 20139 Milan, Italy.
Massimo RonchiMedical, Formulation Development and R&D Departments, Indena, S.p.A, Viale Ortles, 12, 20139 Milan, Italy.
Giovanna PetrangoliniMedical, Formulation Development and R&D Departments, Indena, S.p.A, Viale Ortles, 12, 20139 Milan, Italy.ORCID 0000-0001-6681-7329
Eric De CombarieuMedical, Formulation Development and R&D Departments, Indena, S.p.A, Viale Ortles, 12, 20139 Milan, Italy.
Silvia TurroniUnit of Microbiome Science and Biotechnology, Department of Pharmacy and Biotechnology, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0003-2345-9482
Gabriele ContiHuman Microbiomics Unit, Department of Medical and Surgical Sciences, University of Bologna, 40126 Bologna, Italy.ORCID 0000-0002-4623-043X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

clinical trialCronilief™low back painneuropathic painnutraceuticalpalmitoylethanolamidePhytosome™

Identifiers

PMID41751279
PMCPMC12937724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.