Evidence map›Paper›PMID 41751188›Full record

ReviewBiomedicines2026

Rare Primary Headaches in Children: A Narrative Review.

Edvige Correnti, Sofia D'Agostino, Federica Cernigliaro, Floriana Ferro, Giulia Manfrè, Caterina Gaspari, Carola Meo, Mariarita Capizzi, Giuseppe Giglia, Vittorio Sciruicchio and 1 more

Abstract readReview
In one paragraph

Review in Biomedicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Edvige CorrentiChild Neuropsychiatry Department, ISMEP, ARNAS Civico, 90127 Palermo, Italy.
Sofia D'AgostinoChild Neuropsychiatry Department, ISMEP, ARNAS Civico, 90127 Palermo, Italy.
Federica CernigliaroChild Neuropsychiatry Department, ISMEP, ARNAS Civico, 90127 Palermo, Italy.
Floriana FerroChild Neuropsychiatry Department, ISMEP, ARNAS Civico, 90127 Palermo, Italy.
Giulia ManfrèChild Neuropsychiatry Department, ISMEP, ARNAS Civico, 90127 Palermo, Italy.
Caterina GaspariChild Neuropsychiatry Department, ISMEP, ARNAS Civico, 90127 Palermo, Italy.
Carola MeoChild Neuropsychiatry Department, ISMEP, ARNAS Civico, 90127 Palermo, Italy.
Mariarita CapizziChild Neuropsychiatry Department, ISMEP, ARNAS Civico, 90127 Palermo, Italy.
Giuseppe GigliaDepartment of Biomedicine, Neuroscience and Advanced Diagnostics (BIND), Section of Human Physiology, University of Palermo, 90134 Palermo, Italy.ORCID 0000-0001-5616-3595
Vittorio SciruicchioChildren Epilepsy and EEG Center, San Paolo Hospital, ASL Bari, 70132 Bari, Italy.ORCID 0000-0003-2388-573X
Vincenzo RaieliChild Neuropsychiatry Unit Department, Pro.MI.S.E. "G. D'Alessandro", University of Palermo, 90127 Palermo, Italy.ORCID 0000-0001-6149-0881

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Headache is a very common disorder in children and adolescents. While migraine and tension headaches are well-known and diagnosed by pediatricians, a group of primary headaches in children, rare in frequency, are poorly understood and likely underestimated by physicians, resulting in delayed diagnosis and treatment. This review aims to provide an updated overview of these clinical forms, considering new evidence. We will present the main clinical, therapeutic, and pathophysiological aspects and possible future hypotheses, with specific reference to pediatric cases of the following clinical forms: cough headache, thunderclap headache, cold headache, primary stabbing headache, nummular headache, hypnic headache, red ear syndrome, and non-odontogenic orofacial pain. These clinical forms currently pose a major diagnostic challenge for pediatricians and represent a source of serious disability for children and adolescents.

Indexed as

childrenheadachesinternational headache classificationmigraineorofacial painpediatric casered ear syndrome

Identifiers

PMID41751188
PMCPMC12938338

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.