Evidence map›Paper›PMID 41751174›Full record

ArticleBiomedicines2026

ACE-Dependent Alzheimer's Disease: Blood ACE Phenotyping of the Most Prevalent and Damaging

Anastasiia A Buianova, Ivan A Adzhubei, Olga V Kryukova, Olga A Kost, Iaroslav V Mironenko, Alex S Kozuch, Galit A Ilyina, Anna A Kuznetsova, Zhanna A Repinskaia, Alexey V Churov and 3 more

Abstract read
In one paragraph

Article in Biomedicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Anastasiia A BuianovaGenomics Laboratory, Pirogov Russian National Research Medical University, 117513 Moscow, Russia.ORCID 0000-0001-7894-9222
Ivan A AdzhubeiDepartment of Biomedical Informatics, Harvard Medical School, Boston, MA 02115, USA.ORCID 0000-0002-1483-9259
Olga V KryukovaDepartment of Chemistry, M.V. Lomonosov Moscow State University, 119991 Moscow, Russia.ORCID 0009-0005-1051-1642
Olga A KostDepartment of Chemistry, M.V. Lomonosov Moscow State University, 119991 Moscow, Russia.ORCID 0000-0001-9665-0523
Iaroslav V MironenkoInstitute on Aging Research, Russian Clinical Research Center of Gerontology, Pirogov Russian National Research Medical University, Ministry of Healthcare of the Russian Federation, 129226 Moscow, Russia.ORCID 0009-0003-4108-1214
Alex S KozuchDepartment of Medicine, Division of Pulmonary, Critical Care, Sleep and Allergy, University of Illinois at Chicago, Chicago, IL 60612, USA.
Galit A IlyinaGenomics Laboratory, Pirogov Russian National Research Medical University, 117513 Moscow, Russia.
Anna A KuznetsovaGenomics Laboratory, Pirogov Russian National Research Medical University, 117513 Moscow, Russia.ORCID 0009-0009-5168-0927
Zhanna A RepinskaiaGenomics Laboratory, Pirogov Russian National Research Medical University, 117513 Moscow, Russia.ORCID 0009-0007-4228-6114
Alexey V ChurovInstitute on Aging Research, Russian Clinical Research Center of Gerontology, Pirogov Russian National Research Medical University, Ministry of Healthcare of the Russian Federation, 129226 Moscow, Russia.ORCID 0000-0002-3920-7581
Steven M DudekDepartment of Medicine, Division of Pulmonary, Critical Care, Sleep and Allergy, University of Illinois at Chicago, Chicago, IL 60612, USA.ORCID 0000-0001-5624-0714
Denis V RebrikovGenomics Laboratory, Pirogov Russian National Research Medical University, 117513 Moscow, Russia.ORCID 0000-0002-1884-1807
Sergei M DanilovDepartment of Medicine, Division of Pulmonary, Critical Care, Sleep and Allergy, University of Illinois at Chicago, Chicago, IL 60612, USA.ORCID 0000-0002-6901-4545

Funding

Ministry of Health of the Russian Federation 1025082100015-5-3.2.21M.V. Lomonosov Moscow State University 121041500039-8
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ACE sheddingAlzheimer ’s diseaseangiotensin I-converting enzymegenetic modifiersplasma ACE levelsprotective variantstransport-deficient mutations

Identifiers

PMID41751174
PMCPMC12937726

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.