Evidence map›Paper›PMID 41751164›Full record

ArticleBiomedicines2026

Use of Small-Molecule Inhibitors of CILK1 and AURKA as Cilia-Promoting Drugs to Decelerate Medulloblastoma Cell Replication.

Sean H Fu, Chelsea Park, Niyathi A Shah, Ana Limerick, Ethan W Powers, Cassidy B Mann, Emily M Hyun, Ying Zhang, David L Brautigan, Sijie Hao and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sean H FuDepartment of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA.
Chelsea ParkDepartment of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA.
Niyathi A ShahDepartment of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA.
Ana LimerickDepartment of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA.
Ethan W PowersDepartment of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA.
Cassidy B MannDepartment of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA.
Emily M HyunDepartment of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA.
Ying ZhangDepartment of Microbiology, Immunology and Cancer Biology, University of Virginia, Charlottesville, VA 22908, USA.
David L BrautiganDepartment of Microbiology, Immunology and Cancer Biology, University of Virginia, Charlottesville, VA 22908, USA.ORCID 0000-0003-1687-5250
Sijie HaoAdvanced Microscopy Facility, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.ORCID 0000-0002-0303-2492
Roger AbounaderDepartment of Microbiology, Immunology and Cancer Biology, University of Virginia, Charlottesville, VA 22908, USA.
Zheng FuDepartment of Pharmacology, University of Virginia, Charlottesville, VA 22908, USA.ORCID 0000-0003-1238-6695

Funding

Calcium Channels in GlioblastomaR01NS122222 · NINDS · UNIVERSITY OF VIRGINIA · PI Roger Abounader · 2022 to 2026
$2.5M
Signaling Mechanisms and Cellular Functions of a Ciliopathy-Associated Protein KinaseR01GM127690 · NIGMS · UNIVERSITY OF VIRGINIA · PI Zheng Fu · 2018 to 2026
$2.4M
NIGMS NIH HHS R01 GM127690NIH HHS 5R01GM127690-06NIH HHS 5R01NS122222-04NINDS NIH HHS R01 NS122222
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AlisertibAlvocidibcancerciliogenesisdrugkinaselarge language model (LLM)natural language processing (NLP)primary cilia

Identifiers

PMID41751164
PMCPMC12938322

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.