Metagenomic Insights into the Modulatory Effects of Thiamine Supplementation for Treating Subclinical Ketosis Dairy Cows.

Fuguang Xue, Fan Zhang, Qinghao Zhuang, Ling Jiang, Mengjie Sun, Jinliang Shang, Benhai Xiong

Abstract read

In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Fuguang XueSchool of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.ORCID 0000-0001-6998-7999

Fan ZhangInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China.

Qinghao ZhuangSchool of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.

Ling JiangSchool of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.

Mengjie SunSchool of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.

Jinliang ShangSchool of Animal Science and Technology, Jiangxi Agricultural University, Nanchang 330045, China.

Benhai XiongInstitute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing 100193, China.

Funding

Integrated Demonstration of Intelligent Feeding and Environmental Control Technologies for Cattle and Sheep 2024YFD1300600Natural Science Foundation Project of Jiangxi Province 20242BAB20311

6 · The paper itself

Abstract

(1) Background: The objective of this study was to investigate the modulatory effects of thiamine on BHBA metabolism, milk yield, and the rumen microbial ecosystem. (2) Methods: A total of 24 SCK dairy cows with similar body conditions were selected and randomly allocated to SCK (SCK) or SCK with thiamine supplement (SCKT) treatment. Twelve healthy dairy cows served as the control (CON) treatment. Milk yield, milk quality, ruminal fermentability parameters, rumen and fecal microbial communities were further measured. (3) Results: Thiamine significantly decreased BHBA content, milk CFUs, and somatic cells, while significantly increasing milk yield, milk fat, acetate, and the A/P ratio (

Indexed as

beta-hydroxybutyratedairy cowsearly lactationsubclinical ketosisthiamine

Identifiers

PMID41751141

DOI10.3390/ani16040680

PMCPMC12937452

What OpenQuestion holds

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.