Evidence map›Paper›PMID 41751098›Full record

ArticleAnimals : an open access journal from MDPI2026

Association of Acute-Phase Proteins and IgG with Bovine Respiratory Disease, Seroconversion to Respiratory Infections and Farm-Level Factors in Rearing Calves.

Rohish Kaura, Elisabeth Dorbek-Sundström, Leena Seppä-Lassila, Vera Talvitie, Jarkko Oksanen, Ulla Rikula, Tuomas Herva, Kerli Mõtus, Timo Soveri, Heli Simojoki and 1 more

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rohish KauraInstitute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Kreutzwaldi 62, 51006 Tartu, Estonia.ORCID 0000-0003-3364-338X
Elisabeth Dorbek-SundströmInstitute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Kreutzwaldi 62, 51006 Tartu, Estonia.ORCID 0000-0002-2274-4188
Leena Seppä-LassilaDepartment of Production Animal Medicine, University of Helsinki, Paroninkuja 20, 04920 Saarentaus, Finland.ORCID 0000-0002-3751-7092
Vera TalvitieDepartment of Production Animal Medicine, University of Helsinki, Paroninkuja 20, 04920 Saarentaus, Finland.
Jarkko OksanenMunicipal Veterinarian, Oulu Environment Office, Solistinkatu 2, 90140 Oulu, Finland.
Ulla RikulaVirology Research Unit, Department of Animal Diseases and Food Safety Research, Finnish Food Authority Ruokavirasto, Mustialankatu 3, 00790 Helsinki, Finland.
Tuomas HervaAtria Ltd., AtriaBeef, Mikkolantie 16, 90310 Oulu, Finland.
Kerli MõtusInstitute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Kreutzwaldi 62, 51006 Tartu, Estonia.ORCID 0000-0003-0080-4378
Timo SoveriDepartment of Production Animal Medicine, University of Helsinki, Paroninkuja 20, 04920 Saarentaus, Finland.
Heli SimojokiDepartment of Production Animal Medicine, University of Helsinki, Paroninkuja 20, 04920 Saarentaus, Finland.
Toomas OrroInstitute of Veterinary Medicine and Animal Sciences, Estonian University of Life Sciences, Kreutzwaldi 62, 51006 Tartu, Estonia.ORCID 0000-0002-4895-8029

Funding

Estonian Research Council IUT8-1European Agricultural Fund for Rural Development KESTOMercedes Zachariassen foundation N.A
6 · The paper itself

Abstract

This study investigated the associations between acute-phase proteins (APPs) such as serum amyloid A (SAA), haptoglobin (Hp), and albumin (Alb) as well as immunoglobulin G (IgG) with bovine respiratory disease (BRD), seroconversion to respiratory infections and farm-level factors in rearing calves. Datasets were obtained from a randomised trial of 476 calves in Finland that compared morbidity in large- versus small-group housing. Calves were assessed for clinical BRD, and their blood was sampled three times during the first 50 rearing days to measure APPs and IgG concentrations and virus-specific antibodies against

Indexed as

acute-phase proteinsbovine respiratory diseasecalfIgG

Identifiers

PMID41751098
PMCPMC12937341

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.