Evidence map›Paper›PMID 41751079›Full record

ArticleAnimals : an open access journal from MDPI2026

Characterization of the Endometrial Microbiota of Healthy Mares Across the Estrous Cycle.

Gian Guido Donato, Denis Necchi, Fabrizia Gionechetti, Ugo Ala, Patrizia Nebbia, Patrizia Robino, Maria Cristina Stella, Hilde Vandaele, Alberto Pallavicini, Tiziana Nervo

Abstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gian Guido DonatoDepartment of Veterinary Sciences, University of Turin, 10095 Grugliasco, Italy.
Denis NecchiKeros Embryo Transfer Center, 8980 Passendale, Belgium.
Fabrizia GionechettiDepartment of Life Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0002-7255-3865
Ugo AlaDepartment of Veterinary Sciences, University of Turin, 10095 Grugliasco, Italy.ORCID 0000-0001-5408-6397
Patrizia NebbiaDepartment of Veterinary Sciences, University of Turin, 10095 Grugliasco, Italy.ORCID 0000-0002-9256-0413
Patrizia RobinoDepartment of Veterinary Sciences, University of Turin, 10095 Grugliasco, Italy.ORCID 0000-0002-0033-0662
Maria Cristina StellaDepartment of Veterinary Sciences, University of Turin, 10095 Grugliasco, Italy.ORCID 0000-0002-1931-0872
Hilde VandaeleKeros Embryo Transfer Center, 8980 Passendale, Belgium.
Alberto PallaviciniDepartment of Life Sciences, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0001-7174-4603
Tiziana NervoDepartment of Veterinary Sciences, University of Turin, 10095 Grugliasco, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the past, bacteria detected in the mare's uterus were generally interpreted as a sign of endometritis, since the uterus was considered a sterile environment. This assumption has been challenged by the introduction of culture-independent molecular techniques, particularly 16S rRNA amplicon sequencing, which have demonstrated that healthy mares harbor an endometrial microbiota. The aim of this study was to characterize the endometrial microbiota of healthy mares and to determine whether microbial composition differs between estrus and diestrus. Endometrial samples were collected from eleven healthy Standardbred mares during estrus and diestrus and analyzed by sequencing the V1-V2 region of the bacterial 16S rRNA gene. A total of 24 bacterial phyla and 599 genera were identified. At the phylum level, Firmicutes, Proteobacteria, Bacteroidota, and Actinobacteriota accounted for most of the relative abundance, while the most abundant genera were

Indexed as

endometriumestrous cyclehorsemaremicrobiotauterus

Identifiers

PMID41751079
PMCPMC12937484

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.