ArticleAnimals : an open access journal from MDPI2026
Alveolar and Airway Components of the Tidal Volume in Mechanically Ventilated Dogs: An Exploratory Cross-Sectional Study.
Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundTidal volume (VT) during mechanical ventilation in dogs varies considerably between individuals, but the contributions of airway dead space (VDaw) and alveolar tidal volume (VTalv) to this variability remain unclear.
methodsIn this prospective, observational, exploratory study, 95 anesthetized dogs receiving volume-controlled ventilation with VT initially set at 15 mL kg
resultsVTalv accounted for a greater proportion of the observed VTe variability than VDaw, indicating that interindividual differences in VTalv were the primary determinant of VT variability. Brachycephalic dogs exhibited smaller VDaw but similar VTalv compared with non-brachycephalic dogs. Ideal body weight was correlated with proportionally higher VDaw and lower VTalv. Recumbency was not correlated with the observed variability in VT components.
conclusionsVTalv was the main determinant of VT variability among anesthetized dogs, and the brachycephalic breeds studied exhibited smaller VDaw but similar VTalv compared with non-brachycephalic breeds. These findings highlight the importance of considering VTalv and breed-specific airway anatomy when individualizing ventilatory settings.
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