Surfactin-Induced β-(1,3)-Glucan Exposure in

Bo Zhang, Lingzhi Zhang, Zhengjun Pang, Wenshuo Zhang, Fenghuan Wang, Junfeng Fan, Bolin Zhang

Abstract read

In one paragraph

Article in Foods (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bo ZhangKey Laboratory of Digital-Intelligence and Dynamic Perception for Food Quality of China Light Industry, Beijing Technology and Business University, Beijing 100048, China.

Lingzhi ZhangKey Laboratory of Digital-Intelligence and Dynamic Perception for Food Quality of China Light Industry, Beijing Technology and Business University, Beijing 100048, China.

Zhengjun PangKey Laboratory of Digital-Intelligence and Dynamic Perception for Food Quality of China Light Industry, Beijing Technology and Business University, Beijing 100048, China.

Wenshuo ZhangKey Laboratory of Digital-Intelligence and Dynamic Perception for Food Quality of China Light Industry, Beijing Technology and Business University, Beijing 100048, China.

Fenghuan WangKey Laboratory of Digital-Intelligence and Dynamic Perception for Food Quality of China Light Industry, Beijing Technology and Business University, Beijing 100048, China.ORCID 0000-0003-2498-3673

Junfeng FanBeijing Key Laboratory of Forest Food Processing and Safety, Department of Food Science and Engineering, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China.

Bolin ZhangBeijing Key Laboratory of Forest Food Processing and Safety, Department of Food Science and Engineering, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083, China.ORCID 0000-0002-6746-493X

Funding

National Natural Science Foundation of China 22378005Research Foundation for Youth Scholars of Beijing Technology and Business University RFYS2025

6 · The paper itself

Abstract

Fruit spoilage caused by fungal pathogens jeopardizes food safety and inflicts significant economic damage. Cyclic lipopeptides (CLPs) have been applied as biofungicides by disrupting the cell membrane and intracellular components; however, the first target for antifungal action is the fungal cell wall. This study elucidates the molecular mechanism by which CLPs compromise cell wall integrity using molecular dynamics simulation and experimental validation. Among Surfactin C, Iturin A, and Fengycin A, Surfactin C exhibited the strongest binding to β-glucan (ΔE = -1970.536 kcal/mol) and the lowest free volume (7.302%), with enhanced effects at higher concentrations. Key interaction sites were identified at C=O of D-Leu3, -N-H of Leu2, and -COOH of Glu1 by Radial distribution function. In vivo assays with

Indexed as

binding energycell wallmolecular dynamics simulationsurfactinβ-(1,3)-glucan

Identifiers

PMID41750980

DOI10.3390/foods15040788

PMCPMC12941012

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.