ArticleAntioxidants (Basel, Switzerland)2026
Short-Term Consumption of Low-Molecular Weight Polyphenols (Oligonol) Is Associated with Improved Post-Exercise Recovery in Healthy Young Men: A Randomized Single-Blind Crossover Study.
Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Polyphenols have been suggested to aid exercise recovery through antioxidant properties, but their efficacy remains controversial, partly due to limited bioavailability. This study investigated whether low-molecular weight polyphenols (LMWPs, oligonol) influence metabolic responses related to fatigue and oxidative stress during and after a maximal exercise test in healthy young men. A randomized, single-blind crossover design includes a placebo, a single dose of LMWP (S-LMWP), and 5-day LMWP (5-LMWP) intervention with ≥2-week washouts. Ten eligible participants completed all conditions. Exercise performance, fatigue-related metabolic parameters, and oxidative stress markers were measured before, immediately after, and 30 min after exercise. Heart rate and lactate were additionally assessed for 5 min post-exercise. Exercise performance and anthropometrics did not differ among conditions. However, both LMWP groups showed significantly lower blood lactate at 30 min recovery compared with the placebo group (placebo: 17.09 ± 1.29; S-LMWP: 8.36 ± 0.73; 5-LMWP: 9.18 ± 0.60;
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