Evidence map›Paper›PMID 41750594›Full record

ArticleAntioxidants (Basel, Switzerland)2026

Disruption of Calcium Homeostasis in Human Spermatozoa: Implications on Mitochondrial Bioenergetics, ROS Production, Phosphatidylserine Externalization, and Motility.

Anita Bravo, Ignacio Jofré-Fernández, Rodrigo Boguen, Raúl Sánchez, Fabiola Zambrano, Pamela Uribe

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Anita BravoCenter of Translational Medicine-Scientific and Technological Bioresource Nucleus (CEMT-BIOREN), Faculty of Medicine, Universidad de La Frontera, Temuco 4810296, Chile.ORCID 0009-0004-1909-1288
Ignacio Jofré-FernándezScientific and Technological Bioresource Nucleus, BIOREN, Universidad de La Frontera, Temuco 4811230, Chile.ORCID 0000-0002-0142-2446
Rodrigo BoguenLaboratorio de Investigación en Salud de Precisión, Departamento de Procesos Diagnósticos y Evaluación, Facultad de Ciencias de la Salud, Universidad Católica de Temuco, Temuco 4780000, Chile.ORCID 0000-0002-0325-743X
Raúl SánchezCenter of Translational Medicine-Scientific and Technological Bioresource Nucleus (CEMT-BIOREN), Faculty of Medicine, Universidad de La Frontera, Temuco 4810296, Chile.ORCID 0000-0003-4853-4282
Fabiola ZambranoCenter of Translational Medicine-Scientific and Technological Bioresource Nucleus (CEMT-BIOREN), Faculty of Medicine, Universidad de La Frontera, Temuco 4810296, Chile.ORCID 0000-0003-4840-0508
Pamela UribeCenter of Translational Medicine-Scientific and Technological Bioresource Nucleus (CEMT-BIOREN), Faculty of Medicine, Universidad de La Frontera, Temuco 4810296, Chile.ORCID 0000-0001-7358-7541

Funding

Fondo Nacional de Desarrollo Científico y Tecnológico 1230410Fondo Nacional de Desarrollo Científico y Tecnológico 3230085Fundação de Amparo à Pesquisa do Estado de São Paulo - University of La Frontera (FAPESP - UFRO) FPP22-0022University of La Frontera DI23-3007
6 · The paper itself

Abstract

The etiology of male infertility is linked to oxidative stress, which is an imbalance caused by an excess of reactive oxygen species (ROS) that can negatively impact sperm function. It is known that a strong stimulus to induce excessive ROS production by spermatozoa is an intracellular calcium (Ca

Indexed as

Ca2+ overloadcell deathenergy metabolismoxidative stress

Identifiers

PMID41750594
PMCPMC12937956

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.