ReviewAntioxidants (Basel, Switzerland)2026
Interplay Between Oxidative Stress and Inflammation in Aquatic Animals: Mechanisms, Consequences, and Implications for Aquaculture Health.
Review in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- The Inclusion of Supercritical Fluid Extract ofAntioxidants (Basel, Switzerland) · 2026Article
- Natural Antioxidants and Aquatic Animal Health-2nd Edition.Antioxidants (Basel, Switzerland) · 2026Article
- Microbial levan potentiates hepatic retention and antitumor activity of a PEGylated benzimidazole-curcumin nanocomplex through TLR2-FXR/FGF15-associated immunometabolic remodeling in experimental liver cancer.Scientific reports · 2026Article
- Starvation Exacerbates Cold-Induced Synergistic Hepatic Injury inAntioxidants (Basel, Switzerland) · 2026Article
- Vitamin DApplied microbiology and biotechnology · 2026Review
- Article
- Combined Effects of Dietary Astaxanthin and β-Carotene on Antioxidant Status, Pigmentation, Muscle Quality, and Flavor Profile in Male and FemaleAntioxidants (Basel, Switzerland) · 2026Article
- Effects of Dietary Squalene Supplementation on the Growth Performance and Disease Resistance of Largemouth Bass.Veterinary sciences · 2026Article
- Research progress of exosomes in renal ischemia-reperfusion injury.Frontiers in pharmacology · 2026Review
Corrections and comments
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Authors and funding
3 authors.
Funding
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Abstract
Oxidative stress and inflammation are two tightly interconnected processes that shape the physiological and pathological responses of aquatic animals to environmental and pathogenic challenges. Reactive oxygen species (ROS) act as key molecular mediators linking oxidative damage with immune activation, forming a bidirectional amplification loop in which oxidative stress triggers inflammation, and inflammation further enhances ROS production. This vicious cycle disrupts immune homeostasis, damages vital organs such as the liver, intestine, and gills, and ultimately increases disease susceptibility in aquaculture species. Recent studies have revealed that breaking this ROS-inflammation loop through integrated strategies, combining antioxidant enhancement, inflammation modulation, and immune regulation, can significantly improve stress tolerance and survival. Particularly in viral diseases, targeting the ROS-inflammation-virus replication axis has emerged as a promising approach for effective control. This review systematically summarizes the mechanistic crosstalk between oxidative stress and inflammation, highlights their biological consequences, and proposes mechanism-based prevention strategies for sustainable aquaculture health management.
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Registered trials
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