Evidence map›Paper›PMID 41750588›Full record

ArticleAntioxidants (Basel, Switzerland)2026

Accelerated Solvent Extraction as an Alternative for the Recovery of Phenolic Compounds from Chestnut Bur: Optimization of Extraction Conditions.

Ana I Paniagua-García, Lucía Gómez-González, Silvia González-Rojo, Rebeca Díez-Antolínez

Abstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ana I Paniagua-GarcíaCentre of Biofuels and Bioproducts, Agricultural Technological Institute of Castilla y León, Villarejo de Órbigo, 24358 León, Spain.ORCID 0000-0003-4083-271X
Lucía Gómez-GonzálezCentre of Biofuels and Bioproducts, Agricultural Technological Institute of Castilla y León, Villarejo de Órbigo, 24358 León, Spain.
Silvia González-RojoDepartment of Applied Chemistry and Physics, University of León, Campus de Vegazana s/n, 24071 León, Spain.ORCID 0000-0002-9630-4468
Rebeca Díez-AntolínezCentre of Biofuels and Bioproducts, Agricultural Technological Institute of Castilla y León, Villarejo de Órbigo, 24358 León, Spain.ORCID 0000-0001-7604-1886

Funding

Junta de Castilla y León Agrorecovery
6 · The paper itself

Abstract

Chestnut bur (CB) is a solid waste product generated in large quantities during the harvesting of edible fruits. This by-product is rich in total phenolic content (TPC) with high antioxidant properties, making it suitable for use in a variety of industrial applications. In this study, the operational variables of accelerated solvent extraction (ASE) and conventional solvent extraction (CSE) of CB were optimized in order to obtain extracts with maximum levels of TPC. The analysis revealed that the extract obtained by ASE using 31.3% ethanol at 180 °C for 9 min achieved the highest value of TPC (8.37 ± 0.05 g gallic acid equivalents (GAE)/100 g dry matter (DM)). Moreover, this extract exhibited higher values of radical-scavenging activity for α,α-diphenyl-β-picrylhydrazyl (DPPH) (90.8 ± 0.3%) than those observed for catechin standard (88.7 ± 0.2%). In addition, its phenolic composition revealed high amounts of gallic acid (13.22 ± 1.01 mg/g DM), followed by 3,4-dihydroxybenzoic acid (2.96 ± 0.16 mg/g DM). This study demonstrates the potential for valorization of CB by ASE under feasible extraction conditions, thereby promoting the circular economy.

Indexed as

accelerated solvent extractionchestnut burgallic acidoptimizationphenolic compounds

Identifiers

PMID41750588
PMCPMC12937611

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.