Evidence map›Paper›PMID 41750386›Full record

ArticleBiomolecules2026

Structural and Computational Analysis of

Lalith Perera, Libertad García-Villada, Andrea M Kaminski, Natalya Degtyareva, Lars C Pedersen, Paul W Doetsch

Abstract read
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Lalith PereraGenomic Integrity & Structural Biology Laboratory, NIEHS, Durham, NC 27709, USA.ORCID 0000-0003-0823-1631
Libertad García-VilladaGenomic Integrity & Structural Biology Laboratory, NIEHS, Durham, NC 27709, USA.ORCID 0000-0001-9796-9341
Andrea M KaminskiGenomic Integrity & Structural Biology Laboratory, NIEHS, Durham, NC 27709, USA.ORCID 0000-0002-6263-4186
Natalya DegtyarevaGenomic Integrity & Structural Biology Laboratory, NIEHS, Durham, NC 27709, USA.ORCID 0000-0002-7141-6308
Lars C PedersenGenomic Integrity & Structural Biology Laboratory, NIEHS, Durham, NC 27709, USA.ORCID 0000-0002-4488-4077
Paul W DoetschGenomic Integrity & Structural Biology Laboratory, NIEHS, Durham, NC 27709, USA.ORCID 0000-0003-3195-3413

Funding

Crystallographic studies of macromolecular structuresZICES102645 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI PEDERSEN, LARS · 2018 to 2025
$12.6M
Mechanisms of transcriptional and replicative mutagenesisZIAES103328 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI DOETSCH, PAUL · 2018 to 2025
$10.5M
Mass Spectrometry QuantitationZICES103005 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI WILLIAMS, JASON · 2018 to 2025
$9.2M
Macromolecular ModelingZICES043010 · NIEHS · NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES · PI COPELAND, WILLIAM · 2012 to 2025
$5.7M
NIH HHS ZIA ES103328NIH HHS ZIC ES043010NIH HHS ZIC ES102645NIH HHS ZIC ES103005
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

CiprofloxacinDNA GyraseDrug Resistance, BacterialPseudomonas aeruginosaAnti-Bacterial AgentsCatalytic DomainMolecular Dynamics SimulationMutationAnti-Bacterial AgentsCiprofloxacinDNA Gyraseantibiotic resistance mechanismsciprofloxacin resistancecrystal structureDNA damagefluoroquinolonesgyrasemolecular dynamics simulationsPseudomonas aeruginosa

Identifiers

PMID41750386
PMCPMC12938007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.