Evidence map›Paper›PMID 41750382›Full record

ArticleBiomolecules2026

Evaluation of GlcNAc-Configured Glycomimetics as Pharmacological Chaperones of NAGLU for the Treatment of Mucopolysaccharidosis IIIB.

Nissrine Ballout, Jérôme Désiré, Angela Johana Espejo-Mojica, Katherin Niño-Traslaviña, Daniel Sandoval, Carlos Javier Alméciga-Díaz, Yves Blériot, Jérôme Ausseil

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nissrine BalloutToulouse Institute for Infectious and Inflammatory Diseases (Infinity), University of Toulouse, Inserm U1291, CNRS U5051, 31024 Toulouse, France.ORCID 0000-0001-8301-3170
Jérôme DésiréOrganic Synthesis Team, Glycochemistry Group, IC2MP UMR CNRS 7285, Université of Poitiers, 86073 Poitiers Cedex 9, France.ORCID 0000-0003-1076-3610
Angela Johana Espejo-MojicaInstitute for the Study of Inborn Errors of Metabolism, Faculty of Science Pontificia Universidad Javeriana Cra. 7 No. 43-82 Building 54, Lab 305A, Bogotá 110231, Colombia.ORCID 0000-0001-9670-6435
Katherin Niño-TraslaviñaInstitute for the Study of Inborn Errors of Metabolism, Faculty of Science Pontificia Universidad Javeriana Cra. 7 No. 43-82 Building 54, Lab 305A, Bogotá 110231, Colombia.
Daniel SandovalDogma Biotech, Bogotá 110231, Colombia.ORCID 0009-0008-3503-1145
Carlos Javier Alméciga-DíazInstitute for the Study of Inborn Errors of Metabolism, Faculty of Science Pontificia Universidad Javeriana Cra. 7 No. 43-82 Building 54, Lab 305A, Bogotá 110231, Colombia.ORCID 0000-0001-6484-1173
Yves BlériotOrganic Synthesis Team, Glycochemistry Group, IC2MP UMR CNRS 7285, Université of Poitiers, 86073 Poitiers Cedex 9, France.ORCID 0000-0002-3209-9282
Jérôme AusseilToulouse Institute for Infectious and Inflammatory Diseases (Infinity), University of Toulouse, Inserm U1291, CNRS U5051, 31024 Toulouse, France.ORCID 0000-0002-3059-9777

Funding

Institute for the Study of Inborn Errors of Metabolism grant number 120289301011ZZSanfilippo Children's Foundation 012023
6 · The paper itself

Abstract

The interaction of a set of four

Indexed as

AcetylglucosamineAcetylglucosaminidaseMucopolysaccharidosis IIICell LineFibroblastsGlycosaminoglycansHumansMolecular Docking SimulationAcetylglucosamineAcetylglucosaminidasealpha-N-acetyl-D-glucosaminidaseGlycosaminoglycansglycomimeticsmucopolysaccharidosis IIIBN-acetyl-glucosaminidase (NAGLU)pharmacological chaperone therapy (PCT)

Identifiers

PMID41750382
PMCPMC12938346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.