Evidence map›Paper›PMID 41750268›Full record

ArticleBiomolecules2026

Microbial Synthesis and Biological Activity of 20β-Hydroxylated Progestins: Ovarian and Neural Action of 17α,20β,21α-Trihydroxy-4-Pregnen-3-One in

Vyacheslav V Kollerov, Vsevolod V Pavshintsev, Alexey V Kazantsev, Andrei A Shutov, Aleksey A Vatlin, Nikita A Mitkin, Olga V Fadeeva, Maxim L Lovat, Elena O Morgun, Marina V Donova

Abstract read
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Vyacheslav V KollerovFederal Research Center «Pushchino Center for Biological Research» of Russian Academy of Sciences, G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Prospekt Nauki, 5, 142290 Pushchino, Russia.ORCID 0000-0002-5623-2930
Vsevolod V PavshintsevInstitute of Environmental Engineering, RUDN University, 6 Miklukho-Maklaya Street, 117198 Moscow, Russia.
Alexey V KazantsevChemical Department, Moscow State University, GSP-1, Leninskiye Gori, 1, 119991 Moscow, Russia.
Andrei A ShutovFederal Research Center «Pushchino Center for Biological Research» of Russian Academy of Sciences, G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Prospekt Nauki, 5, 142290 Pushchino, Russia.ORCID 0000-0002-9501-8072
Aleksey A VatlinInstitute of Environmental Engineering, RUDN University, 6 Miklukho-Maklaya Street, 117198 Moscow, Russia.
Nikita A MitkinCollagel LLC, Belovezskaya 55, 121353 Moscow, Russia.ORCID 0000-0002-1014-9250
Olga V FadeevaInstitute of Mitoengineering MSU LLC, Leninskie Gory, 1, Bld. 73, 119234 Moscow, Russia.
Maxim L LovatDepartment of Neurobiology, Faculty of Biology, Moscow State University, Leninskiye Gori, 1, 119234 Moscow, Russia.ORCID 0000-0002-7949-7974
Elena O MorgunInstitute of Biomedicine, Pirogov Russian National Research Medical University, Ostrovityanova Street, 1, 117997 Moscow, Russia.ORCID 0009-0009-9699-1438
Marina V DonovaFederal Research Center «Pushchino Center for Biological Research» of Russian Academy of Sciences, G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Prospekt Nauki, 5, 142290 Pushchino, Russia.ORCID 0000-0002-9917-8428

Funding

Ministry of Science and Higher Education of the Russian Federation No. 125041005029-5 on the theme FMRM-2025-0032RUDN University Scientific Projects Grant System No. 202789-2-000
6 · The paper itself

Abstract

In this study, the biocatalytic activity of four steroid-transforming strains isolated from the African frog

Indexed as

OvaryProgestinsStreptomycesZebrafishAnimalsBiotransformationFemaleHydroxyprogesteronesXenopus laevis17,20-dihydroxy-4-pregnen-3-oneHydroxyprogesteronesProgestins20β-reductionactinomycetesbiological activitycortexoloneDanio rerioPgrprogestinsStreptomyces rocheiteleosts

Identifiers

PMID41750268
PMCPMC12938133

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.