Evidence map›Paper›PMID 41750267›Full record

ReviewBiomolecules2026

Bioinformatics-Driven, Plant-Based Antibiotic Research Against Quorum Sensing and Biofilm Formation in

Serena Rosignoli, Elisa Lustrino, Olga Shevchuk, Serena Rinaldo, Elisabetta Rubini, Alessandro Paiardini, Ivana Carev

Abstract readReview
In one paragraph

Review in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Serena RosignoliCentre for Regenerative Medicine "Stefano Ferrari", Department of Life Sciences, University of Modena and Reggio Emilia, 41125 Modena, Italy.ORCID 0000-0002-0164-8998
Elisa LustrinoDepartment of Biochemical Sciences "A. Rossi Fanelli", University Sapienza, P. le Aldo Moro 5, 00185 Rome, Italy.
Olga ShevchukGroup of Immunoproteomics, Department of Immunodynamics, Institute for Experimental Immunology and Imaging, University Duisburg-Essen, 45141 Essen, Germany.ORCID 0000-0003-1150-7344
Serena RinaldoDepartment of Biochemical Sciences "A. Rossi Fanelli", University Sapienza, P. le Aldo Moro 5, 00185 Rome, Italy.ORCID 0000-0003-0682-023X
Elisabetta RubiniDepartment of Biochemical Sciences "A. Rossi Fanelli", University Sapienza, P. le Aldo Moro 5, 00185 Rome, Italy.ORCID 0000-0002-1596-5740
Alessandro PaiardiniDepartment of Biochemical Sciences "A. Rossi Fanelli", University Sapienza, P. le Aldo Moro 5, 00185 Rome, Italy.ORCID 0000-0001-9078-7545
Ivana CarevFaculty of Chemistry and Technology, University of Split, 21000 Split, Croatia.

Funding

European Research Council HOLO-GT 101019289Ministero dell'Istruzione e del Merito 2022N3JXLA
6 · The paper itself

Abstract

Quorum-sensing (QS) systems play a crucial role in regulating virulence, biofilm formation, and antibiotic resistance in clinically relevant microbes. This review explores the potential of QS systems as targets for developing novel plant-based therapeutic strategies using bioinformatics, aimed at combating highly pathogenic bacteria: uropathogenic

Indexed as

Anti-Bacterial AgentsBiofilmsComputational BiologyEscherichia coliPseudomonas aeruginosaQuorum SensingDrug Resistance, Multiple, BacterialAnti-Bacterial Agentsantibioticsantimicrobial resistancebiofilm formationbioinformaticsEscherichia coliPseudomonas aeruginosaquorum sensing (QS)UPEC

Identifiers

PMID41750267
PMCPMC12938168

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.