Evidence map›Paper›PMID 41749987›Full record

ArticleBehavioral sciences (Basel, Switzerland)2026

The Relationship Between Emotion Processing Assessed by an Affect Rating Task and Depression Symptoms Following the Accelerated Sequential Dorsolateral-Dorsomedial Prefrontal rTMS Treatment.

Ruiqin Chen, Zerun Dong, Ruijie Geng, Haibin Li, Yuan Wang, Yuanyuan Li, Qiong Ding, Yingying Zhang, Xuechen Ding, Jingjing Huang and 4 more

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In one paragraph

Article in Behavioral sciences (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ruiqin ChenClinical Research Center for Mental Disorders, Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University, Shanghai 200124, China.
Zerun DongClinical Research Center for Mental Disorders, Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University, Shanghai 200124, China.
Ruijie GengDepartment of Psychological Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Haibin LiDepartment of Psychological Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China.ORCID 0000-0002-4215-1283
Yuan WangDepartment of Psychological Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Yuanyuan LiDepartment of Psychological Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Qiong DingDepartment of Psychiatry, University of Cambridge, Cambridge CB2 0QQ, UK.
Yingying ZhangInstitute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai 200433, China.
Xuechen DingDepartment of Psychology, Shanghai Normal University, Shanghai 200234, China.ORCID 0000-0002-2271-2506
Jingjing HuangClinical Research Center for Mental Disorders, Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University, Shanghai 200124, China.
Hui ZhaoClinical Research Center for Mental Disorders, Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University, Shanghai 200124, China.
Wenjuan LiuDepartment of Psychological Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Valerie VoonInstitute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai 200433, China.
Yi-Jie ZhaoClinical Research Center for Mental Disorders, Shanghai Pudong New Area Mental Health Center, School of Medicine, Tongji University, Shanghai 200124, China.ORCID 0000-0002-2202-8376

Funding

New Quality Clinical Specialty Program of High-end Medical Disciplinary Construction in Shanghai Pudong New Area 2025-PWXZ-08Science and Technology Development Fund Of Shanghai Pudong New Area PKJ2024-Y33The Scientific Research Program of Shanghai Pudong New Area Health Commission (the Youth Program) PW2025B-13the STI 2030 - Major Projects 2021ZD0200407Tongji University Medicine-X Interdisciplinary Research Initiative 2025-0708-ZD-02
6 · The paper itself

Abstract

backgroundEmotion processing is critical in the neuropathology of major depressive disorder (MDD), while its relationship with clinical treatment remains unclear. This study aims to indicate the associations between emotion processing and treatment effects following a sequential dual-site accelerated repetitive transcranial magnetic stimulation (rTMS) protocol.

methodsMDD patients were recruited to receive rTMS treatment with four sessions per day for four consecutive days, with stimulation sequentially delivered to the left dorsolateral prefrontal cortex (dlPFC) and the dorsomedial prefrontal cortex (dmPFC). Symptoms were assessed at baseline, end of treatment, and week 4 using the Montgomery-Åsberg Depression Rating Scale (MADRS), Snaith-Hamilton Pleasure Scale (SHAPS), and Fatigue Severity Scale (FSS). Emotional valence and arousal were evaluated with the Affect Rating Task (ART).

resultsA total of 51 participants completed the clinical assessments and ART, with two excluded due to missing baseline data in the SHAPS and FSS. The linear mixed-effects models revealed significant improvement in depressive (

conclusionsOur study highlights the association between changes in emotional arousal and improvement in MDD following accelerated dlPFC-dmPFC dual-site rTMS treatment.

Indexed as

accelerated rTMSaffectAffect Rating Task (ART)emotionmajor depressive disorderpredictor

Identifiers

PMID41749987
PMCPMC12938265

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.