Evidence map›Paper›PMID 41749837›Full record

ArticleCancers2026

Autologous Stem Cell Transplantation in HIV-Positive and HIV-Negative Patients with Lymphoma: A Propensity Score-Matched Comparative Analysis.

Alessandro Re, Margherita Oberti, Armando Stabile, Angelo Andreini, Chiara Cattaneo, Chiara Pagani, Salvatore Casari, Maria Antonia Forleo, Cristina Tecchio, Camillo Almici and 4 more

Abstract read
In one paragraph

Article in Cancers, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Alessandro ReUOC di Ematologia, ASST Spedali Civili di Brescia, 25123 Brescia, Italy.ORCID 0000-0003-1156-6395
Margherita ObertiUOC di Ematologia, ASST Spedali Civili di Brescia, 25123 Brescia, Italy.
Armando StabileIRCCS Ospedale San Raffaele, Vita-Salute, Università San Raffaele, 20132 Milano, Italy.
Angelo AndreiniUOC di Ematologia, Azienda Ospedaliera Universitaria Integrata Verona, 37122 Verona, Italy.
Chiara CattaneoUOC di Ematologia, ASST Spedali Civili di Brescia, 25123 Brescia, Italy.ORCID 0000-0003-0031-3237
Chiara PaganiUOC di Ematologia, ASST Spedali Civili di Brescia, 25123 Brescia, Italy.
Salvatore CasariDivision of Infectious Disease, ASST Spedali Civili di Brescia, 25123 Brescia, Italy.
Maria Antonia ForleoDivision of Infectious Disease, ASST Spedali Civili di Brescia, 25123 Brescia, Italy.
Cristina TecchioUOC di Ematologia, Azienda Ospedaliera Universitaria Integrata Verona, 37122 Verona, Italy.ORCID 0000-0002-4001-1607
Camillo AlmiciImmunoematologia e Medicina Trasfusionale, ASST Spedali Civili di Brescia, 25123 Brescia, Italy.ORCID 0000-0002-9438-2569
Alessandra TucciUOC di Ematologia, ASST Spedali Civili di Brescia, 25123 Brescia, Italy.ORCID 0000-0003-3052-7463
Francesco CastelliDivision of Infectious Disease, ASST Spedali Civili di Brescia, 25123 Brescia, Italy.ORCID 0000-0001-9161-7804
Giuseppe RossiUOC di Ematologia, ASST Spedali Civili di Brescia, 25123 Brescia, Italy.ORCID 0000-0001-8377-2898
Mauro KramperaUOC di Ematologia, Azienda Ospedaliera Universitaria Integrata Verona, 37122 Verona, Italy.ORCID 0000-0002-7280-2040

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesTreatment of HIV-associated lymphoma (HIV-Ly) with autologous stem cell transplantation (ASCT) has shown a surprisingly low relapse rate in several series. The aim of this study was to compare the clinical outcomes of HIV-Ly and lymphomas in the general population receiving ASCT.

methodsWe compared two series of consecutive HIV-positive and HIV-negative patients, based on a 1:1 propensity score analysis, matching for age, sex, histology, disease status and prior therapies.

resultsAfter propensity matching we identified a final population of 88 patients (44 HIV-positive vs. 44 HIV-negative). All HIV-positive patients received combination antiretroviral therapy (cART). With a median follow-up of 51 months, PFS was significantly higher in HIV-positive patients (4-year PFS 81% and 51%, in HIV-positive and HIV-negative patients, respectively,

conclusionsOur results clearly show that ASCT is an effective curative option for HIV-Ly, with better PFS and a lower relapse rate compared to patients without HIV. A favorable effect of ASCT on HIV infection and immune system recovery, potential off-target effects of cART or other yet unknown factors may account for this observation.

Indexed as

autologous stem cell transplantationHIVlymphoma

Identifiers

PMID41749837
PMCPMC12939142

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.