Evidence map›Paper›PMID 41749767›Full record

ReviewBioengineering (Basel, Switzerland)2026

A Review of Motion-Preserving Cervical Spinal Implants and Fusion Constructs.

Isabella Merem, Rodrigo Vasquez, Jaden Wise, Elizabeth Beaulieu, Samip Patel, Maohua Lin, Gui Pires, Frank D Vrionis

Abstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Isabella MeremCollege of Medicine, Florida Atlantic University, Boca Raton, FL 33431, USA.ORCID 0009-0008-2110-1499
Rodrigo VasquezCollege of Medicine, Florida Atlantic University, Boca Raton, FL 33431, USA.ORCID 0009-0009-1017-8308
Jaden WiseCollege of Medicine, Florida Atlantic University, Boca Raton, FL 33431, USA.
Elizabeth BeaulieuCollege of Medicine, Florida Atlantic University, Boca Raton, FL 33431, USA.
Samip PatelCollege of Medicine, Florida Atlantic University, Boca Raton, FL 33431, USA.
Maohua LinDepartment of Biomedical Engineering, Florida Atlantic University, Boca Raton, FL 33431, USA.ORCID 0000-0002-9460-2111
Gui PiresSurGenTec LLC, Boca Raton, FL 33487, USA.
Frank D VrionisDepartment of Neurosurgery, Marcus Neuroscience Institute, Boca Raton Regional Hospital, Boca Raton, FL 33486, USA.ORCID 0009-0006-0259-8618

Funding

Marcus Neuroscience Institution C-24-335
6 · The paper itself

Abstract

Spinal fusion remains a common surgical treatment for degenerative cervical spine pathology. By eliminating segmental motion, fusion alters spinal biomechanics and redistributes mechanical loads to adjacent levels. These changes contribute to adjacent segment degeneration (ASD). Motion-preserving spinal implants have been developed to address these limitations. Cervical disc arthroplasty (CDA) is the most widely used example. Such devices aim to maintain physiologic kinematics while preserving segmental stability. Their biomechanical behavior varies with implant design, material properties, and constraint characteristics. Previous research does not holistically compare fusion with motion-preserving treatments on the spine, resulting in an incomplete understanding of when motion-preserving devices should be considered in treatment over fusion constructs and which specific motion-preserving implants are most appropriate. This narrative review synthesizes experimental, computational, and clinical studies comparing rigid fusion constructs to motion-preserving technologies in the cervical spine. Emphasis is placed on segmental range of motion, load transmission, intradiscal pressure, facet joint forces, and adjacent-segment mechanics. By comparing effectiveness across motion-preserving treatments, alongside their effectiveness to fusion constructs, we found that CDA more closely preserves near-physiologic motion compared to fusion. Taken together, this review underscores the importance of biomechanics-informed implant design for guiding future innovation in spinal implant technologies.

Indexed as

adjacent segment degenerationcervical spine biomechanicsfinite element analysisload transmissionmotion-preserving spinal implantsrange of motionspinal fusion

Identifiers

PMID41749767
PMCPMC12938692

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.