ArticleBioengineering (Basel, Switzerland)2026
Therapeutic Efficacy of Floating Electrode-Dielectric Barrier Discharge Plasma in Experimental Periodontitis: A Pilot Study.
Article in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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6 authors.
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Abstract
Periodontitis is a chronic inflammatory disease characterized by dysbiotic biofilms and host-mediated destruction of periodontal tissues. This study evaluated the efficacy of a novel needle-shaped floating electrode-dielectric barrier discharge (FE-DBD) plasma probe in treating experimental periodontitis. Using a split-mouth design in a rat model of ligature-induced periodontitis, subgingival microbiome changes were analyzed via 16S rRNA sequencing, while gene expression of inflammatory mediators and osteoclastogenic factors was quantified by qRT-PCR. Histopathological evaluation and osteoclast activity were assessed through H&E and TRAP staining, respectively. FE-DBD treatment significantly shifted the subgingival microbiome by reducing pathobionts such as
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