Evidence map›Paper›PMID 41749736›Full record

ReviewBioengineering (Basel, Switzerland)2026

Applications of 3D Printing and Artificial Intelligence in Healthcare Management: A Narrative Review.

Conrado Domínguez Trujillo, Donato Monopoli Forleo, Carmen Delia Dávila Quintana, Juan Mora Delgado

Abstract readReview
In one paragraph

Review in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Conrado Domínguez TrujilloCanary Islands Health Service, University of Las Palmas de Gran Canaria, 35001 Las Palmas de Gran Canaria, Spain.
Donato Monopoli ForleoDepartment of Biomedical Engineering, Instituto Tecnológico de Canarias, 35003 Las Palmas de Gran Canaria, Spain.
Carmen Delia Dávila QuintanaDepartamento de Métodos Cuantitativos en Economía y Gestión, University of Las Palmas de Gran Canaria, 35017 Las Palmas de Gran Canaria, Spain.ORCID 0000-0002-4608-1040
Juan Mora DelgadoGICAMI (Grupo Investigación Clínico Asistencial de Medicina Interna) Group, Infectious Diseases and Microbiology Unit, Instituto de Investigación e Innovación Biomédica de Cádiz (INiBICA), Hospital Universitario de Jerez de la Frontera, 11407 Jerez de la Frontera, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The integration of 3D printing and artificial intelligence is transforming healthcare management by driving innovations in personalized care, supply chain operations, and clinical workflows. This review offers a comprehensive overview and in-depth analysis of recent (2018-2025) applications where AI technologies enhance 3D printing within healthcare. We explore how AI-powered design and optimization facilitate the creation of patient-specific medical devices, implants, and even bioprinted tissues, while intelligent process control increases both quality and efficiency. Additionally, we examine regulatory and ethical considerations, including the evolution of frameworks for AI-enabled devices, as well as challenges in data governance, validation, and equitable access. The review takes a global perspective, presenting real-world case studies that showcase both successful implementations and ongoing challenges. We also discuss various perspectives and controversies, such as the balance between innovation and safety in autonomous AI design, and highlight areas where further research is needed. In contrast to previous narrative reviews that focus solely on clinical applications or technical aspects, this review uniquely evaluates the combined impact of AI and 3D printing on healthcare management-including cost-effectiveness, governance, decision-making processes, and point-of-care manufacturing. This work is particularly valuable for hospital administrators, clinical operations leaders, health policymakers, and biomedical innovation teams seeking to understand the broader implications of AI-enhanced 3D printing in healthcare management. Nevertheless, despite promising advancements, the field is constrained by heterogeneous evidence, a lack of standardized evaluation metrics, and insufficient long-term outcome data, which together limit the ability to fully assess the sustained impact of AI-integrated 3D printing in healthcare environments.

Indexed as

artificial intelligencebiomedical engineeringbioprintingmachine learningpatient-specific modelingprintingthree-dimensional

Identifiers

PMID41749736
PMCPMC12938761

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.