Evidence map›Paper›PMID 41749634›Full record

ReviewChildren (Basel, Switzerland)2026

Video Game-Based Interventions for Visual Rehabilitation in Childhood Amblyopia: A Systematic Review and Meta-Analysis.

Marina Piñar-Lara, Esteban Obrero-Gaitán, Sara Gómez-Molina, Rafael Lomas-Vega, Héctor García-López, Irene Cortés-Pérez

Abstract readReview
In one paragraph

Review in Children (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Marina Piñar-LaraCAIT APROMPSI, C/Clara Campoamor 8, 23470 Cazorla, Spain.ORCID 0009-0006-0242-7659
Esteban Obrero-GaitánDepartment of Health Sciences, University of Jaén, Campus Las Lagunillas s/n, 23071 Jaén, Spain.ORCID 0000-0002-8430-5500
Sara Gómez-MolinaDiana del Castillo Physiotherapy Centre, C/Pedro Campos Campiña, 5, 2330 Jaén, Spain.
Rafael Lomas-VegaDepartment of Health Sciences, University of Jaén, Campus Las Lagunillas s/n, 23071 Jaén, Spain.ORCID 0000-0003-2546-6301
Héctor García-LópezDepartment of Nursing, Physiotherapy and Medicine, University of Almería, Ctra. Sacramento s/n, La Cañada de San Urbano, 04120 Almería, Spain.ORCID 0000-0003-3160-7692
Irene Cortés-PérezDepartment of Health Sciences, University of Jaén, Campus Las Lagunillas s/n, 23071 Jaén, Spain.ORCID 0000-0002-1876-1399

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNovel approaches such as video games represent a promising tool in increasing visual acuity (VA) in children with amblyopia. The aim was to determine the effectiveness of video game-based interventions (VGBIs) in increasing VA in children with amblyopia. Secondarily, to estimate safety, satisfaction, and compliance with VGBIs.

methodsAccording to the PRISMA guidelines, a systematic review with meta-analysis (SRMA) was conducted, including studies retrieved from PubMed Medline, SCOPUS, WOS, CINAHL, and PEDro without publication date and language restrictions. We included randomized controlled trials (RCTs) and pilot RCTs, comprising children with amblyopia, that compared the effectiveness of VBGI vs. others in improving VA. Pooled effect was estimated with the Cohen's standardized mean difference (SMD) and its 95% confidence interval (95%CI).

resultsTwenty-one RCTs, providing data from 1515 children, were included. VGBIs are effective (SMD = 0.38; 95%CI 0.08 to 0.68;

conclusionThis SRMA, including a large number of RCTs to date, demonstrates that VGBI is effective in improving VA in children with amblyopia.

Indexed as

amblyopiachildrenmeta-analysisvideo gamesvirtual reality-exposure therapyvisual acuityvisual rehabilitation

Identifiers

PMID41749634
PMCPMC12940067

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.