ArticleBMC pediatrics2026
Primordial odontogenic tumor: a case report of a rare entity in the Saudi population.
Article in BMC pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionPrimordial odontogenic tumor (POT) is a rare, benign, mixed epithelial–mesenchymal neoplasm, histologically characterized by spindle- to stellate-shaped cells in a fibromyxoid stroma resembling dental papilla, bordered by columnar epithelium. It occurs mainly in children and adolescents, often in the posterior mandible, and radiographically presents as a well-defined radiolucency associated with unerupted teeth. CASE PRESENTATION: An 18-year-old male presented with asymptomatic swelling of the right mandible. Imaging revealed a well-demarcated unilocular radiolucency extending to the ascending ramus with cortical thinning and perforation. Under a provisional diagnosis of ameloblastoma, right mandibulectomy with plate reconstruction was performed. Histology showed spindle and stellate cells in a delicate collagenous stroma lined by columnar epithelium with reverse nuclear polarity and areas of solid and cystic epithelial proliferation, confirming POT.
conclusionWe report the first case of POT in Saudi Arabia, managed surgically with no recurrence at seven-year follow-up. This case highlights the diagnostic challenges of POT and the importance of continued case documentation to guide recognition and management.
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