Observational studyBMC infectious diseases2026
ECG changes and their utility in adult Vietnamese patients with non-severe dengue.
Observational study in BMC infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
Abstract
backgroundDengue may affect the heart, manifesting as asymptomatic electrocardiographic (ECG) abnormalities to fulminant myocarditis. The role of routine ECG monitoring in dengue management remains unclear. We, therefore, studied ECG changes in patients with non-severe dengue.
methodsIn this observational study, we performed and interpreted 12-lead ECGs (admission, discharge and follow up) on hospitalised Vietnamese adults with confirmed dengue and measured the PR, QRS, and Fridericia-corrected QT intervals (QTcF).
resultsA total of 330 ECGs were performed in 136 patients (64 females; median age, 24 years; range, 16–72 years). Of these, 132 patients had WHO-defined non-severe dengue and 4 had severe dengue. Elevated CK-MB fractions (> 25 IU/L) were detected in 64 of 134 patients (47.8%). The most common ECG abnormality was sinus bradycardia (< 60 beats/min), with 54 episodes occurring in 39 patients (28.7%), most frequently on illness day 10, 9/34 (26.5%) patients. The mean QTcF increased during the first 10 illness days in parallel with a decrease in mean heart rate; only 3 females (461–501 ms) and 1 male (460 ms) had sex-specific QTcF prolongation (≥ 460 ms female, ≥ 450 ms male). Female sex and illness day were significant predictors of QTcF variability over time. Pathological T-wave inversion in the inferior (II, III, aVF) and lateral chest (V5, V6) leads were observed in 12 patients (8.8%), and were mostly transient.
conclusionsECG changes associated with nonsevere dengue in predominantly young Vietnamese adults without comorbidities were mostly mild, non-specific, and transient with limited impact on the QTcF interval. Routine ECGs in non-severe dengue in our setting did not provide clinically actionable information.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.