Evidence map›Paper›PMID 41749130›Full record

ArticleBMC pregnancy and childbirth2026

Relative position of cerclage - an ultrasound marker for prediction of preterm birth.

Laura van der Krogt, Lisa Story, Andrew Shennan, Natalie Suff

Abstract read
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Article in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Laura van der KrogtDepartment of Women and Children's Health, King's College London, St Thomas' Hospital, 10th Floor, North Wing, SE1 7UH 020 7188 3639, London, United Kingdom. laura.c.van_der_krogt@kcl.ac.uk.
Lisa StoryDepartment of Women and Children's Health, King's College London, St Thomas' Hospital, 10th Floor, North Wing, SE1 7UH 020 7188 3639, London, United Kingdom.
Andrew ShennanDepartment of Women and Children's Health, King's College London, St Thomas' Hospital, 10th Floor, North Wing, SE1 7UH 020 7188 3639, London, United Kingdom.
Natalie SuffDepartment of Women and Children's Health, King's College London, St Thomas' Hospital, 10th Floor, North Wing, SE1 7UH 020 7188 3639, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA transvaginal cerclage (TVC) identified high in the cervix is associated with prolongation of pregnancy. However, the relative position of the TVC (length above the cerclage/total cervical length) may be a better predictor of cerclage success as it is proportional of total cervical length. This study evaluates the relative position of TVC and its association with spontaneous preterm birth, comparing its predictive value against other post-cerclage ultrasound parameters.

methodsA retrospective cohort study was conducted of singleton pregnancies with TVC. Demographic and ultrasound data were collected. Differences in TVC characteristics between those who delivered preterm (< 37 weeks) and term, including relative position of cerclage, were assessed using Student’s t-test where data was continuous and chi-squared test where categorical. Receiver operator curves were generated to evaluate predictive performance (SPSS version 29.0).

resultsAmong 53 women, 25% (n = 13) delivered preterm. The relative position of TVC was significantly lower in preterm cases (mean 0.41 versus 0.52, p = 0.024), while total cervical length showed no difference. Length above the TVC was shorter in spontaneous preterm births (mean 11 mm versus 16 mm; p = 0.008). In those who delivered preterm, findings of funnelling and amniotic fluid sludge were more likely to be present after cerclage (p = 0.07 and p = 0.02 respectively). ROC analysis demonstrated good predictive ability for relative position (AUC 0.74) and length above the TVC (AUC 0.73), with an optimal threshold of 0.425 for relative position. Cervical length and cerclage height were poor predictors (AUC 0.43 and 0.59 respectively).

conclusionUltrasound assessment after cerclage can identify women at higher risk of spontaneous preterm birth. Relative position and length above the TVC are good predictors, whereas cervical length and cerclage height are not. Incorporating relative position of TVC position into clinical risk stratification warrants further evaluation.

Indexed as

Cerclage, CervicalCervix UteriPremature BirthUterine Cervical IncompetenceAdultCervical Length MeasurementFemaleHumansPredictive Value of TestsPregnancyRetrospective StudiesROC CurveUltrasonographyUltrasonography, PrenatalCervical cerclageCervical lengthSpontaneous preterm birthUltrasound

Identifiers

PMID41749130
PMCPMC13041413

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.