Evidence map›Paper›PMID 41749120›Full record

ArticleBMC pregnancy and childbirth2026

Breastfeeding practices among hepatitis b-infected mothers: a prospective cohort study.

Yao Lü, Jing Wang, Hongyu Li, Ke Liu, Xia Xiang

Abstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yao Lü *Department of Obstetrics and Gynecology, The First Affiliated Hospital of Army Military Medical University, Chongqing, 400038, China.
Jing Wang *Department of Infection, The First Affiliated Hospital of Army Military Medical University, Chongqing, 400038, China.
Hongyu LiDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Army Military Medical University, Chongqing, 400038, China.
Ke LiuDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Army Military Medical University, Chongqing, 400038, China.
Xia XiangDepartment of Obstetrics and Gynecology, The First Affiliated Hospital of Army Military Medical University, Chongqing, 400038, China. 578697040@tmmu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMother-to-child transmission (MTCT) remains a primary route of Hepatitis B virus (HBV) infection in China. Despite World Health Organisation (WHO) recommendations supporting the safety of breastfeeding under timely immunoprophylaxis, rates among HBV-infected mothers in China remain low.

objectiveTo investigate breastfeeding practices, maternal perceptions, and factors influencing feeding decisions among HBV-infected mothers whose infants received standard immunoprophylaxis.

methodsBetween April 2016 and June 2020, 1,308 infants born to HBsAg-positive mothers were screened. After predefined exclusions, 192 mothers and their infants (n = 194) receiving active–passive immunoprophylaxis (hepatitis B immunoglobulin and a three-dose HBV vaccine) were prospectively followed until 20–30 months postpartum. Infant HBV serology (HBsAg and anti-HBs) was assessed at 7–12 and 20–30 months. Breastfeeding practices, maternal perceptions, and associated factors were analysed using SPSS 22.0.

resultsOf the screened infants, 194 (14.8%) were included in the final cohort. The overall breastfeeding rate was 81.8%, with 45.8% exclusively breastfed. Physician counselling (56.7%), obstetricians (43.0%), and online media (24.8%) were the main information sources. Fear of transmission was the primary reason for not breastfeeding (60.0%). No infant tested positive for HBsAg. Anti‑HBs positivity was 99.5% at 7–12 months and 94.3% at 20–30 months. Physician counselling (aOR = 3.2, 95% CI: 1.7–5.8) and maternity school attendance (aOR = 2.1, 95% CI: 1.1–3.6) independently predicted breastfeeding initiation.

conclusionBreastfeeding is safe with infant immunoprophylaxis and maternal antiviral therapy, yet fear remains a key barrier, highlighting the need for enhanced counseling and support.

Indexed as

Breast FeedingHepatitis BInfectious Disease Transmission, VerticalMothersPregnancy Complications, InfectiousAdultChinaFemaleHealth Knowledge, Attitudes, PracticeHepatitis B Surface AntigensHepatitis B VaccinesHumansInfantInfant, NewbornPregnancyProspective StudiesHepatitis B Surface AntigensHepatitis B VaccinesBreastfeedingChinaHealth educationHepatitis B virusInfant feedingMaternal perceptions

Identifiers

PMID41749120
PMCPMC13077926

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.