Evidence map›Paper›PMID 41749115›Full record

ReviewBMC nephrology2026

Concurrence of renal amyloidosis and membranous nephropathy: a case series and literature review.

Ling Li, Yu Wu, Zhangxue Hu

Abstract readCase ReportsReview
In one paragraph

Review in BMC nephrology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ling LiDepartment of Nephrology, West China Hospital of Sichuan University, Chengdu, 610041, China.
Yu WuDepartment of Hematology, West China Hospital of Sichuan University, Chengdu, 610041, China.
Zhangxue HuDepartment of Nephrology, West China Hospital of Sichuan University, Chengdu, 610041, China. hzxawy@scu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAmyloidosis is a group of heterogeneous diseases characterized by the deposition of amyloid fibrils in various organs and tissues. Membranous nephropathy (MN) is one of the most common causes of nephrotic syndrome in adults. CASE PRESENTATION: We report three cases of early-stage MN occurring concurrently with distinct types of renal amyloidosis: apolipoprotein A-I (AApoA-I) amyloidosis, leukocyte chemotactic factor 2 (ALECT2) amyloidosis, and monoclonal immunoglobulin light-chain (AL) amyloidosis. Each case represents a different pathogenic mechanism, therapeutic approach, and clinical prognosis.

conclusionsThese cases underscore the pivotal role of renal pathology in the accurate diagnosis of patients with coexisting amyloidosis and MN. Correct classification of renal amyloidosis is essential for guiding therapy and predicting outcomes. When amyloidosis coexists with MN or other potentially treatable renal diseases, therapeutic decisions should prioritize the condition with the greater potential for organ damage or the one most responsive to available treatment.

Indexed as

AmyloidosisGlomerulonephritis, MembranousKidney DiseasesAgedFemaleHumansIntercellular Signaling Peptides and ProteinsMaleMiddle AgedIntercellular Signaling Peptides and ProteinsLECT2 protein, humanApolipoprotein A-1 amyloidosisLeukocyte chemotactic factor 2 amyloidosisLight chain amyloidosisMembranous nephropathyPhospholipase A2 receptorRenal amyloidosis

Identifiers

PMID41749115
PMCPMC13040921

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.