Evidence map›Paper›PMID 41749093›Full record

ArticleBMC genomics2026

Transcriptome sequencing reveals iron acquisition-related genes and iron acquisition systems in Auricularia cornea.

Qiushi Zhu, Ming Fang, Fangjie Yao, Lixin Lu, Xiaoxu Ma, Yuling Cui, Xu Sun, Zhen Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC genomics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Qiushi Zhu *Lab of the Genetic Breeding of Edible Mushroom, College of Horticulture, Jilin Agricultural University, Changchun, 130118, China.
Ming Fang *Lab of the Genetic Breeding of Edible Mushroom, College of Horticulture, Jilin Agricultural University, Changchun, 130118, China. fangming@jlau.edu.cn.
Fangjie YaoLab of the Genetic Breeding of Edible Mushroom, College of Horticulture, Jilin Agricultural University, Changchun, 130118, China. yaofj@aliyun.com.
Lixin LuLab of the Genetic Breeding of Edible Mushroom, College of Horticulture, Jilin Agricultural University, Changchun, 130118, China.
Xiaoxu MaLab of the Genetic Breeding of Edible Mushroom, College of Horticulture, Jilin Agricultural University, Changchun, 130118, China.
Yuling CuiEngineering Research Center of Edible and Medicinal Fungi, Ministry of Education, Jilin Agricultural University, Changchun, 130118, China.
Xu SunEngineering Research Center of Edible and Medicinal Fungi, Ministry of Education, Jilin Agricultural University, Changchun, 130118, China.
Zhen WangLab of the Genetic Breeding of Edible Mushroom, College of Horticulture, Jilin Agricultural University, Changchun, 130118, China.

Funding

National Key Research and Development Program of China 2023YFD1201600Variety Transfer Project of Edible Mushroom Variety "Jihei No.2" Approved by Jilin Province 20190122
6 · The paper itself

Abstract

Auricularia cornea exhibits significant potential for iron-enrichment. However, the mechanisms behind iron absorption and accumulation remain poorly understood. This study employed biochemical and transcriptomic approaches to systematically investigate the effects of an iron-rich environment on iron accumulation in A. cornea across 3 growth stages, as well as to characterize its iron acquisition–related (IAR) genes and iron acquisition systems. Our findings showed that A. cornea can produce siderophores. Supplementation with Fe₂(SO₄)₃ markedly increased iron content in both mycelia and primordia. Transcriptomic analysis revealed that iron supplementation significantly altered the expression of key IAR genes during the mycelial stage, but not in the primordia and fruiting body stages. Nine key IAR genes were identified, indicating that A. cornea possesses the molecular basis for the iron accumulation via reductive and non-reductive iron acquisition systems and ferrous transport systems. Phylogenetic analysis revealed that proteins involved in iron transport were highly conserved across Basidiomycota and Ascomycota, whereas those with redox functions have undergone divergence. These results provide new insights into the iron acquisition in A. cornea.

Indexed as

BasidiomycotaGene Expression ProfilingIronTranscriptomeFungal ProteinsGene Expression Regulation, FungalPhylogenySiderophoresFungal ProteinsIronSiderophoresAuricularia corneaIron acquisition systemIron contentSiderophoreTranscriptome

Identifiers

PMID41749093
PMCPMC13041173

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